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Study Finds No Benefit to Taking Fluvoxamine for COVID-19 Symptoms

Study Finds No Benefit to Taking Fluvoxamine for COVID-19 Symptoms

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https://www.newswise.com/coronavirus/study-finds-no-benefit-to-taking-fluvoxamine-for-covid-19-symptoms

Newswise - DURHAM, N.C. - A study led by the Duke Clinical Research Institute (DCRI) in partnership with Vanderbilt University found no symptomatic or clinical benefit to taking the antidepressant fluvoxamine 50 mg twice daily for 10 days for the treatment of mild-to-moderate COVID-19 symptoms. "There was no evidence of improvement in time to recovery in participants who took this dose of fluvoxamine versus those who took a placebo," said Adrian Hernandez, M.D., the study's administrative principal investigator and executive director of the DCRI.


“Other research suggests that 100 mg of fluvoxamine taken twice daily may be effective in treating COVID-19, but tolerance may be a limitation,” said Susanna Naggie, M.D., the DCRI principal investigator overseeing the study’s clinical coordinating center. “We set out to test if 50 mg taken twice daily is effective and tolerated. We learned efficacy is not achieved at the lower dose of fluvoxamine and look forward to learning of and sharing results from the open study arm testing the higher dose.”