Brain motor and fear circuits regulate leukocytes during acute stress - Nature
Source : https://www.nature.com/articles/s41586-022-04890-z
The nervous and immune systems are intricately linked1. Although psychological stress is known to modulate immune function, mechanistic pathways linking stress networks in the brain to peripheral leukocytes remain poorly understood2. Here, we show that distinct brain regions shape leukocyte distribution and function throughout the body during acute stress in mice.
Collectively, these data show that distinct brain regions differentially and rapidly tailor the leukocyte landscape during psychological stress, thus calibrating the immune system’s capacity to respond to physical threats.