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Predictors of type 2 diabetes remission in the Diabetes Remission Clinical Trial (DiRECT)

To identify predictors of type 2 diabetes remission in the intervention arm of DiRECT (Diabetes Remission Clinical Trial). Participants were aged 20-65 years, with type 2 diabetes duration of see more

Source : https://onlinelibrary.wiley.com/doi/abs/10.1111/dme.14395?af=R

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Childhood BMI and Fasting Glucose and Insulin Predict Adult Type 2 Diabetes: The International Childhood Cardiovascular Cohort (i3C) Consortium

OBJECTIVE To examine childhood BMI, fasting glucose, and insulin in relation to incident adult type 2 diabetes mellitus (T2DM). RESEARCH DESIGN AND METHODS We used data from The International Childhood ..... see more

Source : https://care.diabetesjournals.org/content/early/2020/08/31/dc20-0822

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Insulin resistance in type 2 diabetic youth

This review focuses on recent literature on insulin resistance in youth with type 2 diabetes mellitus (T2DM). Insulin resistance is associated with a variety of cardiometabolic problems leading to increased ..... see more

Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296021/

African-American Male with Poorly-Controlled Diabetes

The 70-year-old African-American male patient presents with a diagnosis of type 2 diabetes for the past five years. Since he retired one year ago, ..... see more

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Patterns of changes in serum lipid profiles in prediabetic subjects: results from a 16-year prospective cohort study among first-degree relatives of type 2 diabetic patients

Lipid abnormality pervasively is associated with the risk of type 2 diabetes mellitus. To the best of our knowledge, there is no study that has examined the longitudinal changes in ..... see more

Source : https://lipidworld.biomedcentral.com/articles/10.1186/s12944-020-01371-y

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Dietary strategies to manage diabetes and glycemic control in youth and young adults with youth‐onset type 1 and type 2 diabetes: The SEARCH for diabetes in youth study

Katherine A. Sauder Corresponding Author E-mail address: katherine.sauder@cuanschutz.edu https://orcid.org/0000-0002-8473-8015 Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado, Aurora, Colorado, USA Department of Pediatrics, University of Colorado, School ..... see more

Source : https://onlinelibrary.wiley.com/doi/abs/10.1111/pedi.13091?af=R

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Associations between urinary 6‐sulfatoxymelatonin excretion and diabetic vascular complications or arteriosclerosis in patients with type 2 diabetes

There are limited reports on the association between melatonin levels and vascular complications in patients with type 2 diabetes. The aim of this study was to determine the association between ..... see more

Source : https://onlinelibrary.wiley.com/doi/full/10.1111/jdi.13374

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Device‐measured physical activity and its association with physical function in adults with type 2 diabetes mellitus

This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between ..... see more

Source : https://onlinelibrary.wiley.com/doi/abs/10.1111/dme.14393

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Long-term change in physiological markers and cognitive performance in type 2 diabetes: the Look AHEAD Study

AbstractContext. The effects of physiological improvements on cognitive function among persons with type 2 diabetes mellitus (T2DM) are not fully understood.O see more

Source : https://academic.oup.com/jcem/advance-article-abstract/doi/10.1210/clinem/dgaa591/5897494?redirectedFrom=fulltext

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Vitamin D supplementation for prevention of type 2 diabetes mellitus. To D or not to D?

AbstractContext. Over the last decade, vitamin D has emerged as a risk determinant for type 2 diabetes and vitamin D supplementation has been hypothesized as a see more

Source : https://academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgaa594/5897217

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Dual GIP and GLP‐1 Receptor Agonist, Tirzepatide, Improves Lipoprotein Biomarkers Associated with Insulin Resistance and Cardiovascular Risk in Patients with Type 2 Diabetes

Cookies are disabled for this browser. Wiley Online Library requires cookies for authentication and use of other site features; therefore, cookies must be enabled to browse the site. Detailed information ..... see more

Source : https://dom-pubs.onlinelibrary.wiley.com/doi/abs/10.1111/dom.14174

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Effects Of Fatty Liver On The Size And Composition Of High‐Density Lipoprotein Cholesterol Subpopulations In Adolescents With Type 2 Diabetes Mellitus

This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between ..... see more

Source : https://onlinelibrary.wiley.com/doi/abs/10.1111/pedi.13103

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Associations between retinal microvascular abnormalities and declining renal function in the elderly population: the Cardiovascular Health Study - PubMed

Background: Microvascular abnormalities in the kidney are common histopathologic findings in individuals with chronic kidney disease or renal failure. These abnormalities may represent one manifestation of ongoing systemic microvascular damage. ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/16112039/

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Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity

Recent genome-wide association studies (GWAS) identified DUSP8, a dual-specificity phosphatase targeting MAP kinases, as type 2 diabetes (T2D) risk gene. Here, we unravel Dusp8 as gatekeeper in the hypothalamic control ..... see more

Source : https://www.jci.org/articles/view/136363

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Multi-layered epigenetic regulation of IRS2 expression in the liver of obese individuals with type 2 diabetes

IRS2 is an important molecular switch that mediates insulin signalling in the liver. IRS2 dysregulation is responsible for the phenomenon of selective insulin resistance that is observed in type 2 ..... see more

Source : https://link.springer.com/article/10.1007/s00125-020-05212-6

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Effects Of Fatty Liver On The Size And Composition Of High‐Density Lipoprotein Cholesterol Subpopulations In Adolescents With Type 2 Diabetes Mellitus

This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between ..... see more

Source : https://onlinelibrary.wiley.com/doi/abs/10.1111/pedi.13103

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Associations between retinal microvascular abnormalities and declining renal function in the elderly population: the Cardiovascular Health Study - PubMed

Background: Microvascular abnormalities in the kidney are common histopathologic findings in individuals with chronic kidney disease or renal failure. These abnormalities may represent one manifestation of ongoing systemic microvascular damage. ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/16112039/

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Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity

Recent genome-wide association studies (GWAS) identified DUSP8, a dual-specificity phosphatase targeting MAP kinases, as type 2 diabetes (T2D) risk gene. Here, we unravel Dusp8 as gatekeeper in the hypothalamic control ..... see more

Source : https://www.jci.org/articles/view/136363

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Multi-layered epigenetic regulation of IRS2 expression in the liver of obese individuals with type 2 diabetes

IRS2 is an important molecular switch that mediates insulin signalling in the liver. IRS2 dysregulation is responsible for the phenomenon of selective insulin resistance that is observed in type 2 ..... see more

Source : https://link.springer.com/article/10.1007/s00125-020-05212-6