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Prognostic impact of short-term ambulatory blood pressure variability for microvascular and macrovascular outcomes in patients with type 2 diabetes: the Rio de Janeiro Type 2 Diabetes Cohort Study - PubMed

1 Department of Internal Medicine, University Hospital Clementino Fraga Filho, School of Medicine. 2 Civil Engineering Program, COPPE, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil. 1 Department ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/33239549/

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Parkinson's, cancer, type 2 diabetes share a key element that drives disease - Salk Institute for Biological Studies

LA JOLLA-When cells are stressed, chemical alarms go off, setting in motion a flurry of activity that protects the cell's most important players. During the rush, a protein called Parkin ..... see more

Source : https://www.salk.edu/news-release/parkinsons-cancer-type-2-diabetes-share-a-key-element-that-drives-disease/

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The cross-sectional association of renal dysfunction with tests of cognition in middle-aged adults with early type 2 diabetes: The GRADE Study - PubMed

doi: 10.1016/j.jdiacomp.2020.107805. 1 Kaiser Permanente of Georgia, Division of Endocrinology, Atlanta, GA, United States of America; Division of Endocrinology, Emory University School of Medicine, Atlanta, GA, United States of America. ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/33288412/

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Insulin Secretion is a Strong Predictor for Need of Insulin Therapy in Patients With New Onset Diabetes and HbA1c >10%, a post hoc analysis of EDICT study - PubMed

Insulin secretion in response to a 75-g OGTT predicts the need for insulin therapy at the time of T2DM diagnosis. A cut point of 1.7 of CPEP 120 /CPEP 0 ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/33852204/

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Barriers to retinopathy screening in youth and young adults with type 1 diabetes

Early detection of diabetic retinopathy (DR) is imperative; however, adherence to screening guidelines is poor. We hypothesized that youth and young adults with type 1 diabetes (T1D) who met American ..... see more

Source : https://onlinelibrary.wiley.com/doi/abs/10.1111/pedi.13171

32-Year-Old Female Diagnosed with Type 2 Diabetes

Maria is 32 and was recently diagnosed with Type 2 Diabetes (T2D). Her recent symptoms include frequent urination, thirst, and ..... see more

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  • from PA Unite 1 week 1 day
    Not enough information on this patient. What was her initial BP? Weight? Height? BMI? And what are those values on first follow-up visit? What is her repeat liver panel? Lipid Show More
  • 3 weeks 1 day
    Add januvia 100 qd
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Can circulating miR-7-1-5p, and miR-33a-5p be used as markers of T2D patients?

Abstract Recent evidence has indicated that miRNAs play an important role in both initiation and progression of many pathologic processes such as diabetes and can be used as an important ..... see more

Source : https://doi.org/10.1080/13813455.2021.1871762

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Increased body fat mass reduces the association between fructosamine and glycated hemoglobin in obese type 2 diabetes patients - PubMed

Obesity is increasing in patients with type 2 diabetes. A possible reduced association between fructosamine and glycated hemoglobin (HbA1c) in obese individuals has been previously discussed, but this has never ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/32767822/

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#:~:text="Parkinson's, cancer, type 2,type 2 diabetes also activates." see more

Parkinson's, cancer, type 2 diabetes share a key element that drives disease: Enzyme with central role in cancer and type 2 diabetes also activates

Researchers have discovered a direct link between a master sensor of cell stress and a protein that protects the power stations of cells. The same pathway is also tied to ..... see more

Source : https://www.sciencedaily.com/releases/2021/04/210408112344.htm

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U of A team identifies new approach to tackling heart disease in people with Type 2 diabetes

A University of Alberta laboratory has uncovered a new approach to preventing heart failure in people with Type 2 diabetes, according to research findings published today in the journal Cell ..... see more

Source : https://www.ualberta.ca/folio/2021/04/u-of-a-team-identifies-new-approach-to-tackling-heart-disease-in-people-with-type-2-diabetes.html

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Lower irisin level in patients with type 2 diabetes mellitus: A case-control study and meta-analysis - PubMed

doi: 10.1111/1753-0407.12256. 1 State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing. 2 Department of General Surgery, The Third Affiliated Hospital to Nantong University, Wuxi, China. ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/25494632/

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The prognostic value of the triglyceride glucose index in patients with chronic heart failure and type 2 diabetes: A retrospective cohort study - PubMed

doi: 10.1016/j.diabres.2021.108786. Online ahead of print. 1 Department of Cardiology, Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen, Shenzhen, China. 2 Department of Ambulatory Surgery, Huazhong University of Science and ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/33812901/

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Association of apolipoproteins A1 and B with type 2 diabetes and fasting blood glucose: a cross-sectional study

Background Apolipoprotein (Apo) may be associated with type 2 diabetes (T2D), however, little is known whether or not serum apolipoproteins are correlated with fasting blood glucose (FBG) and the prevalence ..... see more

Source : https://bmcendocrdisord.biomedcentral.com/articles/10.1186/s12902-021-00726-5

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Association of Type 2 Diabetes Mellitus and Glycemic Control With Intracranial Plaque Characteristics in Patients With Acute Ischemic Stroke

Jianrong Xu PhD Corresponding Author Huilin Zhao PhD Corresponding Author Chengcheng Zhu PhD Corresponding Author First published: Type 2 diabetes mellitus (T2DM) has shown to be associated with carotid plaque ..... see more

Source : https://onlinelibrary.wiley.com/doi/10.1002/jmri.27614?af=R

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Lower Insulin Secretion Is Associated with Hippocampal and Parahippocampal Gyrus Atrophy in Elderly Patients with Type 2 Diabetes Mellitus - PubMed

doi: 10.1111/jdi.13554. Online ahead of print. 1 Department of Diabetes and Endocrinology, Yokohama City Minato Red Cross Hospital, 3-12-1 Shin-yamashita, Naka-ku, Yokohama, Kanagawa, 231-8682, Japan. 2 Department of Molecular Endocrinology ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/33783982/

William Ameen, Sai Kolla Commented on a Post
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Advancing oral treatment for Type 2 diabetes

Your obese type 2 diabetes patient, who is 58 years old, has been on metformin, but recent HbA1C levels are around 8.2%, despite attempts at controlling diet and exercise. The patient realizes something must be done and would very much like to maximize A1C reductions with the next option, hoping to achieve levels closer to a goal of 7.0%, if not below that, to avoid having to add multiple further medications. However, the patient hopes to avoid injectable medications if they are not completely necessary. The patient would also like to lose weight.

What medication would you recommend next?

Would your recommendation differ if the patient had a history of atherosclerotic cardiovascular disease?

How would you help this patient stay compliant with your prescribed treatment regimen?

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  • 2 weeks 1 day
    Obviously, one must confirm that the patient is actually taking metformin, and if he can be believed, make sure he's on the maximum tolerable dose, 1000 mg of the extended-release Show More
  • 2 weeks 3 days
    Check his diet in detail, cut down Carbs 50% what he is taking and follow HbA1c. If not controlled, add januvia 50mg once daily
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Association of continuous positive airway pressure compliance with complications in patients with type 2 diabetes and obstructive sleep apn

To explore the association of continuous positive airway pressure (CPAP) compliance with clinical outcomes in patients with type 2 diabetes (T2D) and obstructive sleep apnea (OSA) in a real-world setting. ..... see more

Source : https://jcsm.aasm.org/doi/abs/10.5664/jcsm.9248

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Impact of type 2 diabetes mellitus on left ventricular diastolic function in patients with essential hypertension: evaluation by volume-time curve of cardiac magnetic resonance - PubMed

doi: 10.1186/s12933-021-01262-1. 1 Department of Radiology, West China Hospital, Sichuan University, 37# Guo Xue Xiang, Chengdu, 610041, Sichuan, China. 2 Department of Radiology, Key Laboratory of Birth Defects and Related ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/33766020/

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Circadian clock gene Rev-erb linked to dawn phenomenon in type 2 diabetes

Researchers at Baylor College of Medicine, Shandong University in China and other institutions may have found an explanation for dawn phenomenon, an abnormal increase of blood sugar only in the ..... see more

Source : https://www.bcm.edu/news/circadian-clock-gene-rev-erb-linked-to-dawn-phenomenon-in-type-2-diabetes

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Acute hyperglycaemia leads to altered frontal lobe brain activity and reduced working memory in type 2 diabetes

How acute hyperglycaemia affects memory functions and functional brain responses in individuals with and without type 2 diabetes is unclear. Our aim was to study the association between acute hyperglycaemia ..... see more

Source : https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0247753