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Combining CGM and an Online Peer Support Community for Hispanic Adults with T2D: A Feasibility Study.

Background Previous research has identified that people with type 2 diabetes (T2D) within the Hispanic community would benefit from an online peer support community (OPSC) and continuous glucose monitoring (CGM) ..... see more

Source : https://europepmc.org/article/med/34414787

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Falls in individuals with type 2 diabetes; a cross-sectional study on the impact of motor dysfunction, postural instability and diabetic polyneuropathy - PubMed

Individuals with type 2 diabetes reported a higher number of falls within the preceding year compared to healthy controls, irrespective of the presence of DPN. The main factors associated with ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/33259675/

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Genome-Wide Association Study of lipid traits in youth with type 2 diabetes

AbstractContext. Dyslipidemia is highly prevalent in youth with type 2 diabetes (T2D), yet the pathogenic components of dyslipidemia in youth with T2D are poorl see more

Source : https://academic.oup.com/jes/advance-article/doi/10.1210/jendso/bvab139/6354223

Youth-Onset Type 2 Diabetes Leads to Serious Complications by Early Adulthood

A landmark study on type 2 diabetes in young people, involving researchers from Children's Hospital of Philadelphia (CHOP) and Penn Medicine, has found that those diagnosed during childhood and adolescence ..... see more

Source : https://www.chop.edu/news/youth-onset-type-2-diabetes-leads-serious-complications-early-adulthood

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  • from Endocrinologist Nation 4 weeks 1 day
    Thanks for your valuable input Dr Hamid ! Here is a link to the design of a proposed clinical trial evaluating medical vs Show More
  • 1 month
    Diabetes diagnosis in young age can lead to serious health complications. Researchers found that 67% of participants developed high blood pressure, nearly 55% had kidney disease, and 51% had eye Show More
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Novo Nordisk

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The time is now for this oral T2D therapy

Indications and Usage

RYBELSUS® (semaglutide) tablets 7 mg or 14 mg is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes.

Limitations of Use

  • RYBELSUS® is not recommended as a first-line therapy for patients who have inadequate glycemic control on diet and exercise because of the uncertain relevance of rodent C-cell tumor findings to humans
  • RYBELSUS® has not been studied in patients with a history of pancreatitis. Consider other antidiabetic therapies in patients with a history of pancreatitis
  • RYBELSUS® is not indicated for use in patients with type 1 diabetes

Please scroll below for Important Safety Information or click here for Prescribing Information, including Boxed Warning.

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High-risk coronary artery plaque in asymptomatic patients with type 2 diabetes: clinical risk factors and coronary artery calcium score - Cardiovascular Diabetology

Background High-risk coronary artery plaque (HRP) is associated with increased risk of acute coronary syndrome. We aimed to investigate the prevalence of HRP in asymptomatic patients with type 2 diabetes ..... see more

Source : https://cardiab.biomedcentral.com/articles/10.1186/s12933-021-01350-2

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  • from Endocrinologist Nation 1 month
    Key Points • Conclusion/Relevance: “A high prevalence of HRP [High-risk coronary artery plaque] was detected in this population of asymptomatic T2D. The presence of HRP was associated with a particular patient Show More
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New biomarkers may detect early eye changes that can lead to diabetes-related blindness

New biomarkers found in the eyes could unlock the key to helping manage diabetic retinopathy, and perhaps even diabetes, according to new research conducted at the Indiana University School of ..... see more

Source : https://www.nei.nih.gov/about/news-and-events/news/new-biomarkers-may-detect-early-eye-changes-can-lead-diabetes-related-blindness

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First artificial pancreas trialed for outpatients with type 2 diabetes

An artificial pancreas could soon help people living with type 2 diabetes and who also require kidney dialysis. Tests led by the University of Cambridge and Inselspital, University Hospital of ..... see more

Source : https://medicalxpress.com/news/2021-08-artificial-pancreas-trialed-outpatients-diabetes.html

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  • 1 month
    artificial pancreas has the potential to become a key feature of integrated personalized care for people with complex medical needs
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Time Course of Metabolic, Neuroendocrine, and Adipose Effects During 2 Years of Follow-up After Gastric Bypass in Patients With Type 2 Diabetes

Bariatric surgery is currently the most effective treatment for obesity and its metabolic comorbidities ( 1-3). It is often referred to as "metabolic surgery" ( 4) and is typically performed ..... see more

Source : https://academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgab398/6292255?login=true

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  • 1 month
    early glycemic improvement after RYGB, and adipose factors may promote long-term insulin sensitivity and normoglycemia
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Second-Line Therapy for Type 2 Diabetes Management: The Treatment/Benefit Paradox of Cardiovascular and Kidney Comorbidities - PubMed

Patients with cardiovascular disease, HF, and nephropathy, for whom evidence suggests a greater likelihood of benefiting from GLP-1RA and/or SGLT2i therapy, were less likely to start these drugs. Addressing this ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/34348996/

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  • 1 month
    Addressing treatment or benefit most pronounced in non-White and older patients, may help reduce the morbidity associated with these conditions !

Three-year trajectories of metabolic risk factors predict subsequent long-term mortality in patients with type 2 diabetes - PubMed

doi: 10.1016/j.diabres.2021.108995. Online ahead of print. 1 School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan; Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan; Department of ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/34363863/

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  • from Endocrinologist Nation 1 month 1 week
    Key Points • Conclusion/Relevance: “The combination of multiple clusters for metabolic risk factors trajectories had additive effects on risks for all-cause and expanded CVD mortality in patients with type 2 DM. Show More
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Effect of low glycaemic index or load dietary patterns on glycaemic control and cardiometabolic risk factors in diabetes: systematic review and meta-analysis of randomised controlled trials

Objective To inform the update of the European Association for the Study of Diabetes clinical practice guidelines for nutrition therapy. Design Systematic review and meta-analysis of randomised controlled trials. Data ..... see more

Source : https://www.bmj.com/content/374/bmj.n1651

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High lipoprotein(a) concentrations are associated with lower type 2 diabetes risk in the Chinese Han population: a large retrospective cohort study - Lipids in Health and Disease

Background Lipoprotein (a) [Lp(a)] is a proven independent risk factor for coronary heart disease. It is also associated with type 2 diabetes mellitus (T2DM). However, the correlation between Lp(a) and ..... see more

Source : https://lipidworld.biomedcentral.com/articles/10.1186/s12944-021-01504-x

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Long-Term Complications in Youth-Onset Type 2 Diabetes

Our apologies. An error occurred while setting your user cookie. Please set your browser to accept cookies to continue. NEJM.org uses cookies to improve performance by remembering your session ID ..... see more

Source : https://www.nejm.org/doi/full/10.1056/NEJMoa2100165

Time Course of Metabolic, Neuroendocrine, and Adipose Effects During 2 Years of Follow-up After Gastric Bypass in Patients With Type 2 Diabetes

Bariatric surgery is currently the most effective treatment for obesity and its metabolic comorbidities ( 1-3). It is often referred to as "metabolic surgery" ( 4) and is typically performed ..... see more

Source : https://academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgab398/6292255?login=true

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  • from Endocrinologist Nation 1 month 2 weeks
    Key Points • Conclusion/Relevance: “We propose this order of events: (1) rapid glucose lowering (days); (2) attenuated cortisol axis activity and inflammation and increased parasympathetic tone (weeks); and (3) body fat Show More
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East Asian diet‐mimicking diet plan based on the Mediterranean diet and the Dietary Approaches to Stop Hypertension diet in adults with type 2 diabetes: A randomized controlled trial

Sang-Man Jin , Moon-Kyu Lee , Corresponding Author Division of Endocrinology and Metabolism, Department of Internal Medicine, Soonchunhyang University Gumi Hospital, Soonchunhyang University School of Medicine, Gumi, Korea Correspondence Moon-Kyu ..... see more

Source : https://onlinelibrary.wiley.com/doi/10.1111/jdi.13384

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New Study Reveals Serious Long-Term Complications in Youth-Onset Type 2 Diabetes

Phil Zeitler, MD, PhD, has been treating youth with type 2 diabetes for more than 20 years. He and a team of researchers published a paper today on the TODAY2 ..... see more

Source : https://news.cuanschutz.edu/news-stories/new-study-reveals-serious-long-term-complications-in-youth-onset-type-2-diabetes

Moderate and high intensity exercise improves glycaemia, blood pressure and body composition in menopausal women with type 2 diabetes

ADA, A. D. A. (2019). Introduction: Standards of Medical Care in Diabetes-2019. Diabetes Care, 42(Supplement 1), S1-S2. https://doi.org/10.2337/dc19-Sint01 Albu, J. B., Heilbronn, L. K., Kelley, D. E., Smith, S. R., ..... see more

Source : https://rsdjournal.org/index.php/rsd/article/view/17571

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  • from Endocrinologist Nation 1 month 3 weeks
    Key Points • Conclusion/Relevance: “The data showed that 8 weeks of functional training, regardless of intensity, is an effective strategy to improve glucose control and promote health benefits in post-menopausal women Show More
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Association Between High-Density Lipoprotein Cholesterol and Type 2 Diabetes Mellitus Among Chinese: The Beijing Longitudinal Study of Aging

Background: Contradictory conclusions of association between high-density lipoprotein cholesterol (HDL-C) levels and type 2 diabetes mellitus (T2DM) were reported in different populations. This study aimed to clarify the effect of ..... see more

Source : https://www.researchsquare.com/article/rs-30826/v1

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  • 1 month 3 weeks
    Higher HDL-C levels were independently related to the lower risk of the newly-onset T2DM among the elderly in China.