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Influence of sodium-glucose Co-transporter 2 inhibitors on clinical and biochemical markers of dehydration during the Holy Ramadan

Influence of sodium-glucose Co-transporter 2 inhibitors on clinical and biochemical markers of dehydration during the Holy Ramadan

Source : https://www.sciencedirect.com/science/article/abs/pii/S187140212200220X?via=ihub

Excess glucose excretion and diuresis with sodium-glucose co-transporter 2 inhibitors may cause dehydration during Ramadan. * Clinical and biochemical markers of dehydration existed with sodium-glucose co-transporter 2 inhibitors during Ramadan. * SGLT2 inhibitors induced elevation of urine specific gravity, plasma osmolality, and blood urea nitrogen/creatinine ratio.


Conclusions: Significant clinical and biochemical markers of dehydration were noticed among users of SGLT2i during the Holy Ramadan.


  • September 12, 2022
    Important study to detect the potential alteration of hydration status in adult Muslims with type 2 diabetes mellitus (T2D) who used SGLT2i during Ramadan.