Myocarditis After COVID-19 Vaccine - American College of Cardiology
The following are key points to remember from a viewpoint on myocarditis after the BNT162b2 messenger RNA (mRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine, reporting low incidence and...
Protection by a Fourth Dose of BNT162b2 against Omicron in Israel
Source : https://www.nejm.org/doi/full/10.1056/NEJMoa2201570
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Conclusions: Rates of confirmed SARS-CoV-2 infection and severe Covid-19 were lower after a fourth dose of BNT162b2 vaccine than after only three doses. Protection against confirmed infection appeared short-lived, whereas protection against severe illness did not wane during the study period.
Immune responses support COVID-19 vaccination regardless of when people were infected
Source : https://www.eurekalert.org/news-releases/948792
(Memphis, Tenn.-April 5, 2022) Scientists at St. Jude Children's Research Hospital have evaluated how vaccination against, and infection with, SARS-CoV-2 affects the immune system. The results confirm that immunity by...
Results showed that the order of exposure (whether vaccination or infection came first) determined whether or not the immune response was geared toward the spike protein. mRNA vaccines against SARS-Cov-2 target the spike protein (a part of the virus). Vaccination after infection led to further expansion of spike-specific T cells, whereas...
Risks of deep vein thrombosis, pulmonary embolism, and bleeding after covid-19: nationwide self-controlled cases series and matched cohort study
Source : https://www.bmj.com/content/377/bmj-2021-069590
Objective To quantify the risk of deep vein thrombosis, pulmonary embolism, and bleeding after covid-19. Design Self-controlled case series and matched cohort study. Setting National registries in Sweden. Participants 1 057 174...
Conclusions: The findings of this study suggest that covid-19 is a risk factor for deep vein thrombosis, pulmonary embolism, and bleeding. These results could impact recommendations on diagnostic and prophylactic strategies against venous thromboembolism after covid-19.
Interpretation: Both vulnerable DP and KTR groups are at risk for a strong decline for IgG and RBD antibodies. In KTR, antibody titres peak at a markedly lower level and accelerated antibody decline is mixed with a delayed/increasing IgG, RBD-IgG, or cellular immune response in a 16% fraction of patients. In both populations, immune monitoring...