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This meta-analysis of 32 studies finds a significant association between schizophrenia and increased risk of type 2 diabetes (T2DM), with higher risks observed in females, certain regions, and longer follow-up periods.

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Type 2 diabetes mellitus related sarcopenia: a type of muscle loss distinct from sarcopenia and disuse muscle atrophy - PubMed

Type 2 diabetes mellitus related sarcopenia: a type of muscle loss distinct from sarcopenia and disuse muscle atrophy - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38854688/

Muscle loss is a significant health concern, particularly with the increasing trend of population aging, and sarcopenia has emerged as a common pathological process of muscle loss in the elderly....

This review highlights the differences between sarcopenia, disuse muscle atrophy, and Type 2 Diabetes Mellitus (T2DM)-related sarcopenia, emphasizing the need for further research to improve diagnosis and treatment strategies.

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Metabolic effects of very-low calorie diet, Semaglutide, or combination of the two, in individuals with type 2 diabetes mellitus - PubMed

Metabolic effects of very-low calorie diet, Semaglutide, or combination of the two, in individuals with type 2 diabetes mellitus - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38996661/

VLCD elicited greater short-term losses of weight and fat mass than Semaglutide. Adding VLCD to Semaglutide stimulated further weight loss than Semaglutide alone. The combination did not yield any additive...

VLCD induced greater weight loss than Semaglutide in T2D. Combining both improved beta-cell function but showed no additive weight loss benefits over VLCD alone. Further research on this combination is warranted.

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Integration of a fasting-mimicking diet programme in primary care for type 2 diabetes reduces the need for medication and improves glycaemic control: a 12-month randomised controlled trial - PubMed

Integration of a fasting-mimicking diet programme in primary care for type 2 diabetes reduces the need for medication and improves glycaemic control: a 12-month randomised controlled trial - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38546821/

ClinicalTrials.gov NCT03811587 FUNDING: The project was co-funded by Health~Holland, Top Sector Life Sciences & Health, the Dutch Diabetes Foundation and L-Nutra.

A 12-month RCT found that a monthly 5-day fasting-mimicking diet in type 2 diabetes patients reduced glucose-lowering medication use, improved HbA1c, and led to weight loss, demonstrating safety and efficacy in primary care.

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Face-to-face interventions significantly reduce T2DM incidence and promote normoglycemia in prediabetes. Digital health shows limited effectiveness, while blended interventions offer moderate benefits. Further research is needed to establish digital health's role in T2DM prevention.