Type 2 Diabetes Connect
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Continuous and Flash Glucose Monitoring in Adults at Risk of Type 2 Diabetes: A Scoping Review - PubMed

Continuous and Flash Glucose Monitoring in Adults at Risk of Type 2 Diabetes: A Scoping Review - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/39960213/

Existing published studies deploying glucose monitoring technologies show promise in supporting interventions aimed at preventing T2DM in at-risk adults. Further robust studies are required to confirm the long-term acceptability and...

 

CGM and FGM show promise in preventing type 2 diabetes in at-risk adults by improving glucose control and behaviors, but more high-quality studies are needed to confirm long-term effectiveness and feasibility.

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Continuous Glucose Monitoring Metrics for Pregnancies Complicated by Diabetes: Critical Appraisal of Current Evidence - PubMed

Continuous Glucose Monitoring Metrics for Pregnancies Complicated by Diabetes: Critical Appraisal of Current Evidence - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38606830/

Ascertaining the utility of continuous glucose monitoring (CGM) in pregnancy complicated by diabetes is a rapidly evolving area, as the prevalence of type 1 diabetes (T1D), type 2 diabetes (T2D),...

 

Continuous glucose monitoring improves outcomes in type 1 diabetes pregnancies, but its value in type 2 and gestational diabetes remains unclear, with research needed on targets, metrics, and clinical impact.

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Insulin Resistance in Type 1 Diabetes: Pathophysiological, Clinical, and Therapeutic Relevance - PubMed

Insulin Resistance in Type 1 Diabetes: Pathophysiological, Clinical, and Therapeutic Relevance - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/39998445/

People with type 1 diabetes (T1D) are usually considered to exclusively exhibit β-cell failure, but they frequently also feature insulin resistance. This review discusses the mechanisms, clinical features, and therapeutic...

 

Insulin resistance in type 1 diabetes involves metabolic and autoimmune factors, contributes to complications, and may benefit from targeted treatments like insulin pumps or adjunct therapies, despite current limitations in clinical use.

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ECC5004, an oral small-molecule GLP-1 receptor agonist, showed promising safety, tolerability, and dose-dependent glucose and weight reduction in early trials, supporting its continued development for T2DM and obesity.

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What’s New in T2D? Highlights from the 2025 ADA Guidelines

The 2025 ADA guidelines introduce key updates that reflect the growing need for personalized, comprehensive diabetes care to address a broader patient population. Among the most notable changes, continuous glucose monitoring (CGM) is now recommended beyond insulin-treated individuals, particularly for adults with type 2 diabetes who are on glucose-lowering therapies who may benefit from real-time glucose insights to improve glycemic control and reduce variability. The guidelines also offer strategies to navigate medication shortages, incorporate additional classes of glucose-lowering agents with cardiovascular and renal benefits, and maintain weight-loss pharmacotherapy beyond initial goals to support long-term metabolic health.

As medication selection continues to evolve, the guidelines emphasize a patient-centered approach that prioritizes cardiovascular, renal, and metabolic health. Beyond glucose lowering, clinicians are encouraged to consider therapy combinations with demonstrated benefits in reducing cardiovascular risk, slowing kidney disease progression, and supporting sustained weight management. New cardiovascular findings reinforce the role of SGLT2 inhibitors, expanding their use in both preserved and reduced ejection fraction heart failure. The guidelines likewise encourage careful patient selection and ongoing monitoring for adverse effects. Additionally, lifestyle-based interventions such as structured nutrition plans, physical activity, and behavioral strategies remain core pillars in achieving metabolic targets.

How will these updates shape your management strategies for adults with type 2 diabetes, particularly in integrating advanced monitoring tools and optimizing heart and kidney protection?

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