Meat consumption and incident type 2 diabetes: an individual-participant federated meta-analysis of 1·97 million adults with 100 000 incident cases from 31 cohorts in 20 countries - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39174161/
The EU, the Medical Research Council, and the National Institute of Health Research Cambridge Biomedical Research Centre.
A global meta-analysis of 31 cohorts found higher consumption of red, processed, and poultry meat increases type 2 diabetes risk, reinforcing the public health need to limit meat intake.
Artificial sweeteners and risk of incident cardiovascular disease and mortality: evidence from UK Biobank - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38965574/
Our findings suggest significant or marginally significant associations between artificial sweeteners and CVD and its subtypes (CAD, PAD, and HF). The associations are independent of genetic predisposition and are mediated...
https://pubmed.ncbi.nlm.nih.gov/38965574/
Artificial sweetener intake is linked to higher cardiovascular disease risks, especially in non-obese, non-white individuals, independent of genetics, and largely mediated through type 2 diabetes, warranting cautious consumption.
The effects of interaction between smoking and abdominal obesity on pre-diabetes mellitus - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39779809/
Limited studies have been conducted on the interaction of smoking and abdominal obesity on the risk of pre-diabetes mellitus (PDM) among rural adults in southwest China. The data was obtained...
https://pubmed.ncbi.nlm.nih.gov/39779809/
A 2022 study in rural southwest China found 38.98% PDM prevalence among adults aged 40–79, with smoking and abdominal obesity synergistically increasing PDM risk through significant additive interaction.
Endoplasmic reticulum stress mechanisms and exercise intervention in type 2 diabetes mellitus - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38991302/
Type 2 diabetes mellitus (T2DM) is a metabolic disease primarily characterized by insulin resistance (IR) and insufficient insulin secretion. The unfolded protein response (UPR) overactivation induced by endoplasmic reticulum stress...
Exercise improves Type 2 diabetes by modulating endoplasmic reticulum stress, enhancing insulin sensitivity and secretion. This review highlights exercise’s role in regulating stress pathways and suggests precision exercise therapies.
Effect of 5:2 Regimens: Energy-Restricted Diet or Low-Volume High-Intensity Interval Training Combined With Resistance Exercise on Glycemic Control and Cardiometabolic Health in Adults With Overweight/Obesity and Type 2 Diabetes - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38638032/
These findings suggest that the medically supervised 5:2 energy-restricted diet could provide an alternative strategy for improving glycemic control and that the exercise regimen could improve body composition, although it...
A 12-week 5:2 diet significantly improved glycemic control in type 2 diabetes patients, while exercise better maintained lean mass; both improved adiposity and liver fat, though exercise didn’t affect HbA1c.