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Intense simplified strategy for newly diagnosed type 2 diabetes in patients with severe hyperglycaemia: multicentre, open label, randomised trial - PubMed

Intense simplified strategy for newly diagnosed type 2 diabetes in patients with severe hyperglycaemia: multicentre, open label, randomised trial - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/39406449/

ClinicalTrials.gov NCT03194945.

The intense simplified strategy combining short-term insulin therapy followed by oral agents (linagliptin plus metformin) improved long-term glycaemic control and β cell function in newly diagnosed type 2 diabetes patients.

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SGLT2 Inhibitors - The New Standard of Care for Cardiovascular, Renal and Metabolic Protection in Type 2 Diabetes: A Narrative Review - PubMed

SGLT2 Inhibitors - The New Standard of Care for Cardiovascular, Renal and Metabolic Protection in Type 2 Diabetes: A Narrative Review - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38578397/

A substantial evidence base supports the use of sodium-glucose cotransporter-2 inhibitors (SGLT2is) in the treatment of type 2 diabetes mellitus (T2DM). This class of medicines has demonstrated important benefits that...

SGLT2 inhibitors (SGLT2is) offer glucose-lowering, cardiovascular, renal, and metabolic benefits in type 2 diabetes. Guidelines advocate early use, emphasizing cost-effectiveness, organ protection, and long-term health outcomes with updated prescribing tools.

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Relationship Between Diabetes Mellitus and Periodontal/Peri-Implant Disease: A Contemporaneous Review - PubMed

Relationship Between Diabetes Mellitus and Periodontal/Peri-Implant Disease: A Contemporaneous Review - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38614881/

The prevalence of diabetes mellitus (DM), a major chronic disease and a leading cause of death and disability around the world, is rising. According to the latest data, the global...

The review highlights the bidirectional relationship between diabetes mellitus and periodontal/peri-implant disease, emphasizing the importance of glycaemic control and oral hygiene in preventing and managing these conditions.

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Oral magnesium supplementation does not affect insulin sensitivity in people with insulin-treated type 2 diabetes and a low serum magnesium: a randomised controlled trial - PubMed

Oral magnesium supplementation does not affect insulin sensitivity in people with insulin-treated type 2 diabetes and a low serum magnesium: a randomised controlled trial - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/37922013/

This study was supported by a grant from the Dutch Diabetes Research Foundation (2017-81-014).

This study found that oral magnesium supplementation in individuals with insulin-treated type 2 diabetes and low magnesium levels did not improve insulin sensitivity or glucose control, despite increasing serum magnesium levels.

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Innovative Cardiovascular Research Insights at AHA’s 100th Anniversary

At the American Heart Association’s centennial conference, Dr. Amit Khera, Director of Preventive Cardiology and Professor at UT Southwestern Medical Center, and Dr. John L. Sapp, Assistant Dean of Clinical Research at Dalhousie University, presented key findings. Topics included Tirzepatide’s impact on HFpEF and obesity, the comparison of left atrial appendage closure versus anticoagulation for atrial fibrillation, intensive blood pressure control in diabetes, and insights from the VANISH2 trial on ventricular tachycardia. These findings provide healthcare professionals with evidence-based strategies to advance cardiovascular care.