Dysregulated microRNAs in type 2 diabetes and breast cancer: Potential associated molecular mechanisms
Source : https://pubmed.ncbi.nlm.nih.gov/38983808/
Type 2 diabetes (T2D) is a multifaceted and heterogeneous syndrome associated with complications such as hypertension, coronary artery disease, and notably, breast cancer (BC). The connection between T2D and BC...
Understanding the role of dysregulated miRNAs in T2D and BC could unveil key signaling pathways and biological processes, offering new insights into the link between these conditions and potential therapeutic targets.
Youth-onset Type 2 Diabetes: An Overview of Pathophysiology, Prognosis, Prevention and Management
Source : https://pubmed.ncbi.nlm.nih.gov/38958831/
Youth-onset T2D is increasing in incidence and prevalence worldwide, disproportionately affecting First Nations communities, socioeconomically disadvantaged youth, and people of colour. Youth-onset T2D differs in pathogenesis to later-onset T2D and...
Effective interventions and targeted treatments are urgently needed for youth-onset T2D, considering its rapid progression, severe complications, and impact on mental health, especially in high-risk populations.
Antidiabetic drugs in Parkinson's disease
Source : https://pubmed.ncbi.nlm.nih.gov/39149559/
This review explores the intricate connections between type 2 diabetes (T2D) and Parkinson's disease (PD), both prevalent chronic conditions that primarily affect the aging population. These diseases share common early...
This review highlights shared biochemical pathways between type 2 diabetes and Parkinson's disease, explores antidiabetic drugs as potential PD treatments, and discusses their experimental and clinical efficacy.
Fecal Microbiota Transplantation: A Prospective Treatment for Type 2 Diabetes Mellitus
Source : https://pubmed.ncbi.nlm.nih.gov/38347911/
Dysregulation of GM is closely related to the development of T2DM. Promoting the conversion of GM in T2DM patients to normal population through FMT can reduce insulin resistance and lower...
Dysregulated gastrointestinal microbiome contributes to T2DM. Fecal microbiota transplantation (FMT) shows potential to normalize GM, reduce insulin resistance, and lower blood glucose, but more research is needed.

