Effect of a High-Protein High-Fibre Nutritional Supplement on Lipid Profile in Overweight/Obese Adults with Type 2 Diabetes Mellitus: A 24-Week Randomized Controlled Trial
Source : https://www.hindawi.com/journals/jnme/2021/6634225/
Background . Foods rich in protein and dietary fibre could potentially improve lipid profile in overweight or obese diabetic patients with dyslipidemia and, thereby, mitigate their risk of cardiovascular disease (CVD). In this study, the effect of providing high-protein high-fibre (HPHF) nutritional supplement in addition to standard care of type 2 diabetes mellitus (T2DM) on lipid profile was evaluated.
Conclusion: Twice-daily consumption of a HPHF nutritional supplement significantly improved HDL-C levels. Inclusion of the HPHF supplement would be a useful effective aid for managing dyslipidemia in overweight/obese individuals with T2DM.
• Source: Journal of Nutrition and Metabolism
• Conclusion. “Twice-daily consumption of a HPHF [high-protein high-fiber] nutritional supplement significantly improved HDL-C levels. Inclusion of the HPHF supplement would be a useful effective aid for managing dyslipidemia in overweight/obese individuals with T2DM.”
• In this prospective, randomized study, South Indian investigators assigned 100 overweight/obese diabetic participants to an experimental group receiving 25 g HPHF nutritional supplement given twice daily, along with a standard care of T2DM, or a control group for 24 weeks.
• Researchers noted a significant improvement in HDL-C levels and an increase in protein and fiber intake in the HPHF group. There was no significant change in the TChol/HDL ratio.
• “Even though reduction (LDL-C, TG, and TChol/HDL-ratio) and improvement (HDL-C) in lipid parameters are small, they are sufficient to result in metabolic changes that might be expected to translate into clinical benefits in reducing CVD risk,” wrote the authors.
• The long intervention is a strength of this study. The main limitation is the small sample size
• The authors suggested that combining HPHF nutritional supplements with a diabetic diet, as well as other lifestyle changes, could help control dyslipidemia, which is a risk factor that independently predicts for CVD.
Waist-to-height ratio has a stronger association with cardiovascular risks than waist circumference, waist-hip ratio and body mass index in type 2 diabetes
Source : https://www.sciencedirect.com/science/article/abs/pii/S0168822721005118
Available online 2 December 2021, 109151 To compare the associations between four anthropometric indices including waist-to-height ratio (WHtR), waist circumference (WC), waist-hip-ratio (WHR) and body mass index (BMI) and cardio-cerebrovascular events (CCBVEs) in Chinese T2DM patients. The associations of four anthropometric measures with CCBVEs and metabolic syndrome (MetS) were compared by multiple regression model in 3108 T2DM patients.