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New Drugs to Treat ADHD: Opportunities and Challenges in Research and Development

New Drugs to Treat ADHD: Opportunities and Challenges in Research and Development

Source : https://link.springer.com/chapter/10.1007/7854_2022_332

Since the landmark MTA (Multimodal Treatment of ADHD) trial unequivocally demonstrated the efficacy of methylphenidate, catecholaminergic drugs, especially stimulants, have been the therapeutic mainstay in treatment of Attention-Deficit Hyperactivity Disorder (ADHD). We review the new drugs which have entered the ADHD formulary.



Conclusion: Substantial improvements in ADHD pharmacotherapy have been achieved by the almost exclusive use of once-daily medications and prodrugs, e.g. lisdexamfetamine and Azstarys®, which improve compliance, deliver greater efficacy and reduce risks for diversion and abuse.