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Fun Fact! Statin-associated muscle symptoms (SAMS) occur in 10–29% of patients, typically presenting as myalgia or myositis in the thighs or calves. Severe cases like rhabdomyolysis are rare. Genetic variations, especially in the SLCO1B1 gene, have been linked to a higher risk of developing SAMS during statin treatment.

Could SLCO1B1 genetic testing support safer, more personalized statin prescribing?

 NCCN Guidelines

Could SLCO1B1 genetic testing support safer, more personalized statin prescribing?

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A 12-month RCT will assess if adding group-based nutritional education to standard care improves HbA1c in T2D patients. Covering shopping habits, plate planning, and hunger cues, the program targets glycemic control and broader metabolic outcomes.

Learn more about this patient-centered trial

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Is GLP-1 receptor agonist therapy safe for patients with intraductal papillary mucinous neoplasm? - PubMed

Is GLP-1 receptor agonist therapy safe for patients with intraductal papillary mucinous neoplasm? - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/41100817/

Glucagon-like peptide-1 receptor agonists are increasingly used in the management of obesity and diabetes. Their potential risks, however, particularly regarding pancreatitis and pancreatic cancer, remain contentious. Despite numerous studies and...

This review discusses the uncertain safety of GLP-1 receptor agonists in patients with intraductal papillary mucinous neoplasms (IPMNs), emphasizing the need for targeted studies to clarify pancreatitis and malignancy risks in this population.

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Costs of mental health care resource use in people with obesity: A systematic review - PubMed

Costs of mental health care resource use in people with obesity: A systematic review - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/41061006/

Our findings suggest that people with obesity incur substantial costs related to the use of mental health care, yet less than half of the included COI studies reported mental health...

This systematic review highlights substantial but inconsistently reported mental health care costs among individuals with obesity, emphasizing the need for clearer cost attribution and integrated economic evaluation of obesity–mental health comorbidity.

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Obesity: Prevalence, causes, consequences, management, preventive strategies and future research directions - PubMed

Obesity: Prevalence, causes, consequences, management, preventive strategies and future research directions - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/41041606/

Obesity has emerged as one of the most pressing global public health challenges of the 21st century. Obesity has reached epidemic proportions worldwide, with over 1 billion people classified as...

This comprehensive review examines global obesity trends, underlying genetic, behavioral, and environmental causes, and related non-communicable diseases, emphasizing evidence-based management, prevention strategies, and urgent multisectoral actions to mitigate the growing global obesity epidemic.

 

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