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This study investigates how acute high-intensity exercise affects appetite control in individuals with overweight/obesity, with or without type 2 diabetes, comparing morning vs. late afternoon sessions in a randomized crossover trial.

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Weight loss-independent changes in human growth hormone during water-only fasting: a secondary evaluation of a randomized controlled trial - PubMed

Weight loss-independent changes in human growth hormone during water-only fasting: a secondary evaluation of a randomized controlled trial - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/39991046/

Fasting increased HGH and the HGH changes were independent of weight loss. Basal HGH and fasting-induced HGH changes correlated inversely with cardiometabolic risk factors.Clinical Trial Registration: clinicaltrials.gov, identifier NCT01059760.

A 24-hour water-only fast increased HGH independently of weight loss. Baseline HGH correlated inversely with cardiometabolic risk factors, and individuals with lower baseline HGH showed greater fasting-induced HGH increases and improved insulin resistance.

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Breaking the Silence on Obesity - PubMed

Breaking the Silence on Obesity - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/39802904/

Obesity is a significant global public health concern, and health care providers play a crucial role in addressing it by offering healthy lifestyle counseling and weight management support. Evidence demonstrates...

Obesity care in primary settings is hindered by bias and stigma. This paper promotes inclusive environments and the 5A model to support respectful, effective weight management counseling by healthcare providers.

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Epigenetics of Childhood Obesity - PubMed

Epigenetics of Childhood Obesity - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/39809244/

Future research will undoubtedly discover numerous methylation sites that may be involved in the development of obesity and its comorbidities, especially at a young age. This will contribute to a...

This review explores the epigenetic basis of childhood obesity, highlighting methylation risk scores' potential for predicting obesity-related diseases, though clinical implementation remains challenging despite promising research advancements.

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Neutrophils as indicators of obesity-associated inflammation: A systematic review and meta-analysis - PubMed

Neutrophils as indicators of obesity-associated inflammation: A systematic review and meta-analysis - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/39610288/

Overall, this meta-analysis demonstrates that ANC is a more reliable and stable parameter than NLR for the assessment of obesity-related inflammation, which offers clinicians a novel tool to assist in...

This meta-analysis finds absolute neutrophil count (ANC) to be a more reliable marker than neutrophil-to-lymphocyte ratio (NLR) for obesity-related inflammation, showing stronger correlation with BMI and less variability across studies.

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