1 Institute for Global Health, University College London, London, UK. Electronic address: [email protected] 2 Department of Population Health, New York University Grossman School of Medicine, New York, NY, USA. 3 Centre for Health Economics, University of York, York, UK. 4 Institute for Global Health, University College London, London, UK.
Interpretation: Under the assumption that making PrEP easily accessible for all adults in sub-Saharan Africa in the context of community education leads to risk-informed use, PrEP is likely to be cost-effective in settings with prevalence of HIV viral load greater than 1000 copies per mL among all adults higher than 2%, suggesting the need for implementation of such approaches, with ongoing evaluation.