Risk factors of severe hepatotoxicity among HIV-1 infected individuals initiated on highly active antiretroviral therapy in the Northwest Region of Cameroon - BMC Gastroenterology
Source : https://bmcgastroenterol.biomedcentral.com/articles/10.1186/s12876-022-02305-x
Background Hepatotoxicity due to highly active antiretroviral therapy (HAART) has gained prominent attention since it can be affected by many factors. The aim of this study was to determine the prevalence of hepatotoxicity and related risk factors of severe hepatotoxicity following HAART initiation.
Conclusions: Low BMI, age group of 30–40years, low monthly income, and the use of AZT 3TC NVP regimen identified as risk factors for the development of severe hepatotoxicity should be considered as an important strategy by clinicians in preventing the hepatotoxicity.