Dolutegravir-containing HIV therapy reversibly alters... : AIDS
is emerging evidence of off-target effects and toxicities. Although limited in number, recent reports have highlighted the vulnerability of mitochondria to these toxicities. The aim of the present study is...
Conclusions: Taken together, our observations indicate that DTG-containing regimens negatively impact cellular and mitochondrial health and may be more toxic to mitochondria, even among the generally well-tolerated InSTI-based cART.
Meaning in life, goals, and adherence to antiretroviral treatment in people living with HIV - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36367188/
Patients living with HIV who do not adhere to antiretroviral treatment (ART) have a high viral load, increasing the risk of developing AIDS, as well as new treatment-resistant strains. There...
Conclusion: We conclude that the design of programs to improve ART adherence should promote the establishment of personal development goals and offer tools that allow having a sense of meaning in life to reduce AIDS-related complications.
The Health Gym: synthetic health-related datasets for the development of reinforcement learning algorithms - Scientific Data
Source : https://www.nature.com/articles/s41597-022-01784-7
In recent years, the machine learning research community has benefited tremendously from the availability of openly accessible benchmark datasets. Clinical data are usually not openly available due to their confidential...
Relevance: In recent years, the machine learning research community has benefited tremendously from the availability of openly accessible benchmark datasets. Clinical data are usually not openly available due to their confidential nature. This has hampered the development of reproducible and generalisable machine learning applications in health...
Disparities in Sexually Transmitted Infection/HIV Testing, Contraception, and Emergency Contraception Care Among Adolescent Sexual Minority Women Who Are Racial/Ethnic Minorities
Source : https://www.jahonline.org/article/S1054-139X(22)00621-8/fulltext
Sexual minority women and racial/ethnic minority women in the United States are at increased risk for sexually transmitted infections (STIs) and unintended pregnancy. Yet, we know little about STI/HIV testing...
Discussion: There is an unmet need for improved SRH service delivery for all adolescent women and for services that are not biased by sex of sexual contact(s) and race/ethnicity.
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Conclusion: To strengthen the identification of HIV patients in the window period, appropriate NGS examination and the follow-up of patients' special lifestyle and medical history will help the judgment and treatment of the disease.