Twenty years of Prevention of Mother to Child HIV Transmission: research to implementation at a national referral hospital in Uganda
Source : https://www.ajol.info/index.php/ahs/article/view/230578
Keywords: PMTCT Research; PMTCT Program; sub-Saharan Africa. Background: Over 90% of new paediatric HIV infections are acquired through mother to child transmission. Prevention of mother to child HIV transmission (PMTCT)...
Conclusion: Perinatal HIV prevention clinical trials conducted at MU-JHU provided evidence to inform WHO PMTCT guidelines. MNRH program evaluation demonstrated the significant decline in MTCT rates over the last two decades.
Assessment of cardiovascular risk factors among HIV-infected patients aged 50 years and older in Cameroon
Source : https://www.aimspress.com/article/doi/10.3934/publichealth.2022034
Background Increasing the longevity of people living with HIV (PLHIV) around the world has been accompanied by an increase in the prevalence of cardiovascular disease (CVD) risk factors and morbidity....
Conclusions: Our study indicated an overall risk of cardiovascular events in 10 years is 16.10%, with the main conditional risk factor being hypertriglyceridemia and alcohol consumption, which appeared to triple the risk of CVD among PLHIV.
Similar costs and outcomes for differentiated service delivery models for HIV treatment in Uganda - BMC Health Services Research
Source : https://bmchealthservres.biomedcentral.com/articles/10.1186/s12913-022-08629-4
This cost-outcome study estimated, from the perspective of the service provider, the total annual cost per client on antiretroviral therapy (ART) and total annual cost per client virally suppressed (defined...
Conclusion: These findings support the scale-up of the DSDMs so as to provide an optimal package of client-centred options to meet the range of client situations and needs. Future research could explore the savings to clients, their increased convenience, adherence and treatment success over longer periods of time.
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Conclusions: These data show that routine pharmacy data can act as a highly predictive mechanism for identifying patients at risk of VNS and VF due to nonadherence.
HIV-1 genetic diversity and transmitted drug resistance to integrase strand transfer inhibitors among recently diagnosed adults in Porto Alegre, South Brazil - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36272141/
All 42 ARV-naive individuals were apparently susceptible to INSTIs, included in the Brazilian therapeutic guideline since 2009. To the best of our knowledge, this is the first study to evaluate...
Conclusions: All 42 ARV-naive individuals were apparently susceptible to INSTIs, included in the Brazilian therapeutic guideline since 2009. To the best of our knowledge, this is the first study to evaluate TDRMs against INSTIs in Brazil. The most prevalent HIV-1 subtypes were subtype C, followed by the recombinant BC and subtype B, which is in...