HIV Drug Resistance in Persons Initiating or Re-initiating First-line Antiretroviral Therapy in Paraguay: Results of a National Patient Survey - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35701340/
Nearly one in six patients had PDR in Paraguay's first nationally representative sample. High NNRTI PDR prevalence underscores the need to accelerate the transition to dolutegravir-based first-line ART. Low PDR...
Conclusions: Nearly one in six patients had PDR in Paraguay's first nationally representative sample. High NNRTI PDR prevalence underscores the need to accelerate the transition to dolutegravir-based first-line ART. Low PDR prevalence to tenofovir and emtricitabine is reassuring as these antiretrovirals are part of the WHO-recommended oral...
Evidence synthesis evaluating body weight gain among people treating HIV with antiretroviral therapy - a systematic literature review and network meta-analysis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35706487/
doi: 10.1016/j.eclinm.2022.101412. 1 School of Population and Public Health, University of British Columbia, 2206 E Mall, Vancouver, British Columbia, Canada. 2 RainCity Analytics, Vancouver, Canada. 3 Global HIV, Hepatitis and...
Interpretation: DTG-based regimens lead to larger average weight gains than some other ART regimens and TAF leads to larger average weight gains than all other backbone antiretrovirals. Further research is needed to better understand long-term outcomes and their relationship to other metabolic outcomes.
Comparison of serum cytokine levels in symptomatic and asymptomatic HIV-Leishmania coinfected individuals from a Brazilian visceral leishmaniasis endemic area - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35714136/
Higher serum levels of IL-17A, IL-6, and IL-10 cytokines were observed in symptomatic coinfected individuals but not in asymptomatically infected individuals. More studies among HIV-positive persons are needed to better...
Conclusions: Higher serum levels of IL-17A, IL-6, and IL-10 cytokines were observed in symptomatic coinfected individuals but not in asymptomatically infected individuals. More studies among HIV-positive persons are needed to better understand the role of serum cytokines for prognosis, to define cure and predict VL relapses in VL-HIV...
Magnitude of dual contraceptive method utilization and the associated factors among women on antiretroviral treatment in Wolaita zone, Southern Ethiopia - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35677405/
This study found that a substantial number of mothers did not use dual contraceptive methods. Disclosure to community increases the use of dual contraceptive methods. Integrating the family planning with...
Conclusion/Relevance: There is limited evidence regarding the association between disclosure to community and dual contraceptive utilization. Thus, the aim of this study is to assess the magnitude of dual contraceptive utilization and its associated factors among ART patients in this study area.
Risk factors of severe hepatotoxicity among HIV-1 infected individuals initiated on highly active antiretroviral therapy in the Northwest Region of Cameroon - BMC Gastroenterology
Source : https://bmcgastroenterol.biomedcentral.com/articles/10.1186/s12876-022-02305-x
Background Hepatotoxicity due to highly active antiretroviral therapy (HAART) has gained prominent attention since it can be affected by many factors. The aim of this study was to determine the...
Conclusions: Low BMI, age group of 30–40years, low monthly income, and the use of AZT 3TC NVP regimen identified as risk factors for the development of severe hepatotoxicity should be considered as an important strategy by clinicians in preventing the hepatotoxicity.