Focus on Infectious Disease
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A Sharp Rise in Autoimmune Encephalitis in the COVID-19 Era: A Case Series

A Sharp Rise in Autoimmune Encephalitis in the COVID-19 Era: A Case Series

Source : https://www.cureus.com/articles/130722-a-sharp-rise-in-autoimmune-encephalitis-in-the-covid-19-era-a-case-series

Background: Autoimmune encephalitis was very rare prior to the current pandemic. A sharp rise in cases has been observed from March to August of 2022 in Los Angeles. Such an...



Conclusions: This observation has important implications: (1) We may be entering an era of heightened autoimmune encephalitis. (2) These occurrences may be post-infectious in nature at this point of the pandemic. (3) Mostly GAD and VGKC antibodies have been identified (10 of them), which may point toward a new direction of research from a...

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A Comprehensive Review of the Current Monkeypox Outbreak

A Comprehensive Review of the Current Monkeypox Outbreak

Source : https://www.cureus.com/articles/134246-a-comprehensive-review-of-the-current-monkeypox-outbreak

Monkeypox is a zoonotic disease caused by an orthopoxvirus named monkeypox virus. The virus was identified in 1958, while the first human monkeypox case was discovered in 1970. Monkeypox caused...

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Monkeypox can be controlled by avoiding contact with the cases and vaccinating those at high risk for acquiring the infection and those at high risk for developing severe illness (immune deficient individuals, pregnant women, and children). Our review aims to comprehensively review the current literature regarding Monkeypox, including modes...

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A Sharp Rise in Autoimmune Encephalitis in the COVID-19 Era: A Case Series - PubMed

A Sharp Rise in Autoimmune Encephalitis in the COVID-19 Era: A Case Series - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/36755772/

This observation has important implications: (1) We may be entering an era of heightened autoimmune encephalitis. (2) These occurrences may be post-infectious in nature at this point of the pandemic....



Conclusions: This observation has important implications: (1) We may be entering an era of heightened autoimmune encephalitis. (2) These occurrences may be post-infectious in nature at this point of the pandemic. (3) Mostly GAD and VGKC antibodies have been identified (10 of them), which may point toward a new direction of research from a...

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New compound inhibits influenza virus replication

New compound inhibits influenza virus replication

Source : https://www.uni-bonn.de/en/news/016-2023

To replicate, viruses need a host cell. There they introduce their genetic information in the form of the nucleic acids DNA or RNA. These molecular blueprints are used in the...



The team led by Prof. Hiroki Kato from the Institute of Cardiovascular Immunology at the University Hospital Bonn has identified a compound that inhibits the body's own methyltransferase MTr1, thereby limiting the replication of influenza viruses.

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Exploring immunodominant epitopes of SARS-CoV-2 nucleocapsid protein as a biomarker of exposure - TittlePress

Exploring immunodominant epitopes of SARS-CoV-2 nucleocapsid protein as a biomarker of exposure - TittlePress

Source : https://tittlepress.com/health/2309794/

The nucleocapsid protein (N protein) of SARS-CoV-2 is undeniably a powerful target for the development of diagnostic tools...



Conclusion: The N2-specific IgG titers in post-COVID-19 samples demonstrated the potential of N protein as an exposure biomarker, particularly in sero-surveillance studies.