Discussion: Using daily symptoms data from a prospective trial, we found the natural history of untreated COVID-19 was variable and undulating. Over one-third of participants who experienced symptom resolution for at least 2 consecutive days within the first 4 to 5 weeks of COVID-19 symptoms reported recurrent symptoms. Reported symptoms are...
Association Between Coronavirus Disease 2019 and Acute Complicated Diverticulitis
Background Gastrointestinal manifestations of coronavirus disease 2019 (COVID-19) are increasingly recognized. Through potentially overlapping pathophysiology, co-occurrence of COVID-19 and first-time acute diverticulitis has been reported. Our study aims to further...
Conclusions: Our study indicates that patients diagnosed with first-time acute diverticulitis within 30 days of COVID-19 infection have a high complication rate, most commonly intestinal perforation. Additionally, patients diagnosed with acute diverticulitis at the same time as COVID-19 detection had a significantly elevated rate of...
VV116 versus Nirmatrelvir-Ritonavir for Oral Treatment of Covid-19 - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36577095/
Among adults with mild-to-moderate Covid-19 who were at risk for progression, VV116 was noninferior to nirmatrelvir-ritonavir with respect to the time to sustained clinical recovery, with fewer safety concerns. (Funded...
Conclusions: Among adults with mild-to-moderate Covid-19 who were at risk for progression, VV116 was noninferior to nirmatrelvir–ritonavir with respect to the time to sustained clinical recovery, with fewer safety concerns.
Paxlovid-Induced Symptomatic Bradycardia and Syncope
Source : https://www.cureus.com/articles/132780-paxlovid-induced-symptomatic-bradycardia-and-syncope
Paxlovid (nirmatrelvir/ritonavir) is a game changer in the fight against COVID-19 due to its ease of administration and significant benefits of reducing progression to severe COVID-19, hospitalization, and death. Cardiac...
Conclusions: We hereby report a potential association between Paxlovid use and sinus node dysfunction. More data is needed to support this association, until then caution may be advised while using Paxlovid, especially in patients with a history of vasovagal syncope.
Researchers discover exploiting microbiome bacteria in patients with lung infections improves low oxygen levels
Source : https://medicalxpress.com/news/2023-01-exploiting-microbiome-bacteria-patients-lung.html
Newspaper headlines from the U.S. to the U.K. and most places in between highlight the surge in sick patients suffering from respiratory viruses. The so-called "tripledemic" of lung infections including...
Therefore, the administration of SLAB51 offers a complementary approach to standard care for treating the hypoxia observed during not just COVID-19 infections but other respiratory viruses such as respiratory syncytial virus (RSV) and the flu.