Safety and Health Care Utilization following COVID-19 Vaccination among Adults with Rheumatoid Arthritis - A population-based self-controlled case series analysis
Source : https://pubmed.ncbi.nlm.nih.gov/37778762/
COVID-19 vaccines in RA patients was not associated with an increase in AESI risk or health care utilization after every dose.
COVID-19 vaccines in RA patients was not associated with an increase in AESI risk or health care utilization after every dose.
Impact of short-term ambient air pollution exposure on the risk of severe COVID-19
Source : https://www.sciencedirect.com/science/article/pii/S1001074222004867?via=ihub
Ecological studies suggested a link between air pollution and severe COVID-19 outcomes, while studies accounting for individual-level characteristics ...
These findings highlight the impact of short-term air pollution exposure, particularly for NO2, on COVID-19 severity, and emphasize the significance in mitigating the COVID-19 burden of commitments to improve air quality.
Broad and Potent Neutralizing Antibodies Are Elicited in Vaccinated Individuals Following Delta/BA.1 Breakthrough Infection
Source : https://journals.asm.org/doi/10.1128/mbio.01206-23
With the emergence of SARS-CoV-2 viral variants, there has been an increase in infections in vaccinated individuals. Here, we isolated monoclonal antibodies (mAbs) from individuals experiencing a breakthrough infection (Delta...
Overall, despite broad neutralization of BA.1, BA.2, and BA.4, the convergent RBD mutations in BA.2.75.2, XBB/XBB.1.5, and BQ.1.1 lead to extensive immune evasion to mAbs generated following Delta and BA.1 BTI. Several potent cross-neutralizing mAbs were identified and additional structural studies would provide important insights into how...
Accelerated and Intensified Manufacturing of an Adenovirus-Vectored Vaccine to Enable Rapid Outbreak Response
Source : https://pubmed.ncbi.nlm.nih.gov/37747758/
The Coalition for Epidemic Preparedness Innovations' "100-day moonshot" aspires to launch a new vaccine within 100 days of pathogen identification, followed by large-scale vaccine availability within the "second hundred days."...
This accelerated manufacturing process, along with other advantages such as thermal stability, supports the ongoing value of adenovirus-vectored vaccines as a rapidly adaptable and deployable platform for emergency response.
Design, synthesis, antiviral activities of ferulic acid derivatives
Source : https://www.frontiersin.org/articles/10.3389/fphar.2023.1133655/full
A series of novel ferulic acid derivatives were designed and synthesized, and the twenty-one compounds were evaluated for their antiviral activities against Respiratory syncytial virus (RSV), herpes simplex virus type...
Relevance: A series of novel ferulic acid derivatives were designed and synthesized, and the twenty-one compounds were evaluated for their antiviral activities against Respiratory syncytial virus (RSV), herpes simplex virus type 1 (HSV-1), and enterovirus type 71 (EV71).