Conclusions and Relevance: The findings of this study suggest that preinfection psychological distress may be a risk factor for post–COVID-19 conditions in individuals with SARS-CoV-2 infection. Future work should examine the biobehavioral mechanism linking psychological distress with persistent postinfection symptoms.
Study Finds No Benefit to Taking Fluvoxamine for COVID-19 Symptoms
Newswise - DURHAM, N.C. - A study led by the Duke Clinical Research Institute (DCRI) in partnership with Vanderbilt University found no symptomatic or clinical benefit to taking the antidepressant...
“Other research suggests that 100 mg of fluvoxamine taken twice daily may be effective in treating COVID-19, but tolerance may be a limitation,” said Susanna Naggie, M.D., the DCRI principal investigator overseeing the study’s clinical coordinating center. “We set out to test if 50 mg taken twice daily is effective and tolerated. We...
Severe COVID-19 induces autoantibodies against angiotensin II that correlate with blood pressure dysregulation and disease severity
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544317/
We began by assessing the presence of immunoglobulin G (IgG) antibodies against AngII in the plasma of 221 subjects, among which 115 were hospitalized patients with COVID-19, 58 were control...
Here, we show that a significant proportion of hospitalized patients with COVID-19 developed autoantibodies against AngII, whose presence correlates with lower blood oxygenation, blood pressure dysregulation, and overall higher disease severity. Anti-AngII antibodies can develop upon specific immune reaction to the SARS-CoV-2 proteins Spike or...
Regular use of common cholesterol-lowering drug linked to reduction of COVID-19 severity, risk of death
NEW ORLEANS - Commonly used cholesterol-lowering statins may reduce the risk of death and severity of COVID-19 disease, suggests a study of more than 38,000 patients being presented at the...
“This research illustrates the importance of evaluating medications that could be repurposed to help patients in ways other than their intended use,” said Dr. Crimi. “Our results suggest statins could be an additional cost-effective solution against COVID-19 disease severity and should be studied further.”
Meaning: The results of this study suggest that ambulatory patients with COVID-19, either vaccinated or not, present a clinically relevant increased risk of incident VTE during the acute phase, with the risk pronounced by factors of older age, male sex, obesity, incomplete vaccination, and factor V Leiden thrombophilia.