Focus on Infectious Disease
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Protection and Waning of Natural and Hybrid Immunity to SARS-CoV-2 - PubMed

Protection and Waning of Natural and Hybrid Immunity to SARS-CoV-2 - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/35613036/

Among persons who had been previously infected with SARS-CoV-2 (regardless of whether they had received any dose of vaccine or whether they had received one dose before or after infection),...


Conclusions: Among persons who had been previously infected with SARS-CoV-2 (regardless of whether they had received any dose of vaccine or whether they had received one dose before or after infection), protection against reinfection decreased as the time increased since the last immunity-conferring event; however, this protection was higher...

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Sensitivity and Specificity of a Novel Colony Characteristic for Determination of Methicillin-Resistant Staphylococcus aureus

Sensitivity and Specificity of a Novel Colony Characteristic for Determination of Methicillin-Resistant Staphylococcus aureus

Source : https://www.cureus.com/articles/79906-sensitivity-and-specificity-of-a-novel-colony-characteristic-for-determination-of-methicillin-resistant-staphylococcus-aureus/metrics

Published: June 17, 2022 DOI: 10.7759/cureus.26040 Cite this article as: Agarwal A N, Dallas S D, Mais D D (June 17, 2022) Sensitivity and Specificity of a Novel Colony Characteristic...


Conclusion: T1 morphology has a modest sensitivity with specificity and positive predictive value amongst S. aureus for identification of methicillin resistance at 48 hours. It can be potentially used for the identification of MRSA, especially in resource-limited settings and wherein a molecular test is not repeated if PCR testing has already...

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While other studies have shown benefit from vitamin D in COVID,10 the NIH states insufficient evidence either for or against the use of Vitamin D in COVID.11 I think it is reasonable to give a high dose once in this setting; however, I do not advocate intermittent high-dose vitamin D because of increased risk of fracture and falls.12,13 I do...

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Radiological Finding of Crazy-Paving Pattern in COVID-19 Pneumonia

Radiological Finding of Crazy-Paving Pattern in COVID-19 Pneumonia

Source : https://www.cureus.com/articles/100573-radiological-finding-of-crazy-paving-pattern-in-covid-19-pneumonia/

The recent global pandemic of coronavirus disease 2019 (COVID-19) has brought many radiographic findings in other respiratory disease processes. One of these radiological findings is crazy paving. This paper discusses...



Chest CT showed ground-glass opacities and interlobular septal thickening consistent with a crazy-paving appearance. As part of the common CT findings of patients with active COVID-19 infection, crazy paving should prompt the interpreting radiologist to consider COVID-19 pneumonia as part of the differential.

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Blood and saliva SARS-CoV-2 antibody levels in self-collected dried spot samples - Medical Microbiology and Immunology

Blood and saliva SARS-CoV-2 antibody levels in self-collected dried spot samples - Medical Microbiology and Immunology

Source : https://link.springer.com/article/10.1007/s00430-022-00740-x

We examined the usefulness of dried spot blood and saliva samples in SARS-CoV-2 antibody analyses. We analyzed 1231 self-collected dried spot blood and saliva samples from healthcare workers. Participants filled...



Self-collected dry blood and saliva spot samples combined with the GSP/DELFIA technique comprise a valuable tool to investigate an individual’s immune response to SARS-CoV-2 exposure or vaccination. Saliva IgG has high potential to monitor vaccination response wane, since the sample is non-invasive and easy to collect.