Inclisiran: A Game Changer in a Changing Game?∗

Source : https://www.jacc.org/doi/full/10.1016/j.jacc.2021.01.008

Association between antecedent statin use and decreased mortality in hospitalized patients with COVID-19

Source : https://www.nature.com/articles/s41467-021-21553-1

The coronavirus disease 2019 (COVID-19) can result in a hyperinflammatory state, leading to acute respiratory distress syndrome (ARDS), myocardial injury, and thrombotic complications, among other sequelae. Statins, which are known...

Prestroke Statins Improve Prognosis of Atrial Fibrillation-Associated Stroke through Increasing Suppressor of Cytokine Signaling-3 Levels - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/33684912/

doi: 10.1159/000513767. Online ahead of print. 1 Department of Neurology, Chengdu Second People's Hospital, Chengdu, China, [email protected]. 2 Department of Neurology, Nanchong Central Hospital, Nanchong, China. 3 Department of Neurology,...

Hyperlipidemia: effective disease management with a focus on PCSK9 inhibitors - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/33710845/

Hyperlipidemia is a prevalent condition in the United States and a significant contributor to atherosclerotic cardiovascular disease (ASCVD). ASCVD is a primary cause of morbidity and mortality in the United...

Pooled Patient-Level Analysis of Inclisiran Trials in Patients With Familial Hypercholesterolemia or Atherosclerosis - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/33663735/

These pooled safety and efficacy data show that inclisiran, given twice yearly in addition to maximally tolerated statin therapy with or without other LDL-C lowering agents, is an effective, safe,...