The role of PCSK9 in NAFLD/NASH and therapeutic implications of PCSK9 inhibition - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36193738/
The current evidence from a landscape of preclinical and clinical studies examining the role of PCSK9 in NAFLD shows controversial results. Preclinical studies indicate that PCSK9 associates with NAFLD and...
Expert Opinion: The current evidence from a landscape of preclinical and clinical studies examining the role of PCSK9 in NAFLD shows controversial results. Preclinical studies indicate that PCSK9 associates with NAFLD and nonalcoholic steatohepatitis (NASH) progression in opposite directions. In humans, it has been concluded that the severity of...
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Healthcare Access Among Individuals of Asian Descent in the U.S - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36196100/
1 Department of Medicine, Section of Cardiology, Baylor College of Medicine, Houston, TX. 2 Department of Medicine, Cleveland Clinic Foundation, Cleveland, OH. 3 Division of Medicine, Forrest General Hospital, Hattiesburg,...
Conclusions: Conclusions: Among Asians living in the U.S. with cardiovascular risk factors or ASCVD, Asian Indians and Other Asians are more likely to report delayed care or no care due to cost compared with Chinese.
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The Association Between Vitamin D Levels and the 10-Year Risk of Atherosclerotic Cardiovascular Disease: A Population-Based Study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36178328/
Background: The association between vitamin D levels and atherosclerotic cardiovascular disease (ASCVD) risk remains unclear. In this study, the association between serum 25(OH)D and 10-year ASCVD risk was examined in...
Conclusion: Our data suggest a negative association between vitamin D levels and the predicted 10-year risk of ASCVD. Further studies are required to investigate whether vitamin D supplements could reduce the risk of ASCVD.
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Association of the systemic immune-inflammation index with all-cause mortality in patients with arteriosclerotic cardiovascular disease
Source : https://www.frontiersin.org/articles/10.3389/fcvm.2022.952953/full
ObjectiveSystemic immune-inflammation index (SII), derived from blood cell counts of circulating platelets, neutrophils, and lymphocytes, has been identified as a novel inflammatory and prognostic marker. However, the clinical value of...
Conclusions: An association was detected between the baseline ln-SII and all-cause mortality in a United States ASCVD population. Increased SII is associated with poor survival in individuals with ASCVD.
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Estimated Atherosclerotic Cardiovascular Disease Risk: Disparities and Severe COVID-19 Outcomes (from the National COVID Cohort Collaborative) - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36175254/
Although cardiovascular disease risk factors relate to COVID-19, the association of estimated atherosclerotic cardiovascular disease (ASCVD) risk with severe COVID-19 is not established. We examined the relation of the pooled-cohort...
Conclusions: Although further research is needed, the 10-year ASCVD risk score in adults ages 40 to 79 years may be used to identify those who are at highest risk for COVID-19 complications and for whom more intensive treatment may be warranted.
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