Clinical Aspects of Genetic and Non-Genetic Cardiovascular Risk Factors in Familial Hypercholesterolemia - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35885941/
1 Division of Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary. 2 Division of Endocrinology, Department of Internal Medicine, Faculty of Medicine, University of...
Conclusion: In this review, we summarize the most important genetic and non-genetic factors that might affect the risk prediction and therapeutic strategy in FH through the eyes of clinicians focusing on disorders that might not be in the center of FH research. The review highlights the complexity of FH care and the need of an...
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Cardiac rehabilitation performance predicts 1-year major adverse cardiovascular events - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35904222/
doi: 10.1002/clc.23890. Online ahead of print. 1 Internal Medicine, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA. 2 School of Medicine, University of...
Conclusion: Our proposed CR-score accurately identifies patients at high risk for 1-year MACE following the rehabilitation program. Multicenter validation is required.
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Conclusions: SVI varies across the US states and is associated with prevalent cardiovascular comorbidities and ASCVD, independent of age, race and ethnicity, sex, employment, income, and health care coverage. SVI may be a useful assessment tool for health policy makers and health systems researchers examining multilevel influences on...
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Pleiotropic Benefits of Statins in Cardiovascular Diseases
Source : https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-1873-1978
Drug Res (Stuttg) DOI: 10.1055/a-1873-1978 1 Department of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, India 1 Department of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, India 1...
Relevance: This article examines some of the existing molecular explanations underlying statin pleiotropy and discusses if they have clinical relevance in cardiovascular diseases.
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Long-term efficacy and safety of moderate-intensity statin with ezetimibe combination therapy versus high-intensity statin monotherapy in patients with atherosclerotic cardiovascular disease (RACING): a randomised, open-label, non-inferiority trial
Source : https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00916-3/fulltext
Among patients with ASCVD, moderate-intensity statin with ezetimibe combination therapy was non-inferior to high-intensity statin monotherapy for the 3-year composite outcomes with a higher proportion of patients with LDL cholesterol...
Interpretation: Among patients with ASCVD, moderate-intensity statin with ezetimibe combination therapy was non-inferior to high-intensity statin monotherapy for the 3-year composite outcomes with a higher proportion of patients with LDL cholesterol concentrations of less than 70 mg/dL and lower intolerance-related drug discontinuation or dose...
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