LOGAN-CV: A Prospective Study of a Multifaceted Intervention Targeting United States Clinicians to Improve Guideline-Based Management of Lipid-Lowering Therapy
Source : https://link.springer.com/article/10.1007/s12325-023-02716-6
The 2018 American Heart Association (AHA)/American College of Cardiology (ACC)/Multisociety blood cholesterol guidelines recommend clinicians consider adding non-statin therapy for patients with very high-risk (VHR) atherosclerotic cardiovascular disease (ASCVD) and...
The clinician education modules developed can help in overcoming clinical inertia, support clinicians in providing guideline-based LLT, and enable patients to achieve recommended LDL-C levels.
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Coronary and Extra-Coronary Subclinical Atherosclerosis to Guide Lipid-Lowering Therapy
Source : https://link.springer.com/article/10.1007/s11883-023-01161-8
The most robust evidence for the use of CAC scoring is in select individuals, 40-75 years of age, at borderline to intermediate 10-year ASCVD risk.
Identification of coronary calcium in selected patients is the single best noninvasive imaging modality to identify future ASCVD risk and inform lipid-lowering therapy decision-making.
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Long-Term Mortality in Patients With Severe Hypercholesterolemia Phenotype From a Racial and Ethnically Diverse US Cohort
Source : https://pubmed.ncbi.nlm.nih.gov/37970713/
In a large, diverse cohort of US patients with the severe hypercholesterolemia phenotype, we identified several patient characteristics associated with increased 9-year all-cause mortality and observed a decrease in statin...
In a large, diverse cohort of US patients with the severe hypercholesterolemia phenotype, we identified several patient characteristics associated with increased 9-year all-cause mortality. A significant survival benefit was conferred by lipid-lowering therapy.
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Age-Dependent Association of Metabolic Dyslipidemia With Clinical Expression of Hypertrophic Cardiomyopathy
Source : https://pubmed.ncbi.nlm.nih.gov/37935337/
High triglyceride and low HDL-C levels are associated with a higher incidence of HCM, particularly in young individuals.
High triglyceride and low high-density lipoprotein cholesterol levels, the 2 dyslipidemia-related components of metabolic syndrome, are associated with a higher incidence of clinical HCM.
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High Residual Cardiovascular Risk After Lipid-Lowering: Prime Time for Predictive, Preventive, Personalized, Participatory, and Psycho-Cognitive Medicine
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613690/
As time has come to translate trial results into individualized medical diagnosis and therapy, we analyzed how to minimize residual risk of cardiovascular disease (CVD) by reviewing papers on "residual...
Digital medicine can aid to move forward towards P5 medicine, in terms of prediction through the collection of big data and AI, prevention through monitoring of patient characteristics, and personalized and participatory by involving the patient when carrying wearable devices.
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