Unique features of dyslipidemia in women across a lifetime and a tailored approach to management
Source : https://pubmed.ncbi.nlm.nih.gov/38634109/
Pathophysiology of dyslipidemia varies between men and women and across a woman's lifetime. While increased lipid levels or lipid imbalances are more common in postmenopausal women over age 50, conditions...
Managing dyslipidemia in women involves early screening, lifestyle changes, and pharmacotherapy tailored to achieve guideline-directed LDL-C levels, addressing risks across different life stages and conditions like PCOS and FH.
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Lipid-based eye drop formulations for the management of evaporative dry eyes
Source : https://pubmed.ncbi.nlm.nih.gov/38523013/
Dry eye disease is a progressive prevalent ocular surface disorder that arises from various factors and is characterized by insufficient quality and/or quantity of tears. The underlying pathophysiology is intricate...
Lipid-based eye drops show potential for treating evaporative dry eyes, but further placebo-controlled trials and innovations are needed to optimize formulations and effectiveness in replicating natural tear lipids.
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Lipid-lowering in diabetes: An update
Source : https://pubmed.ncbi.nlm.nih.gov/37945448/
Atherosclerotic cardiovascular disease (ASCVD) is accelerated in people with diabetes. Dyslipidemia, hyperglycemia, oxidative stress, and inflammation play a role via a variety of mechanisms operative in the artery wall. In...
Effective management of dyslipidemia in T2DM patients is crucial to prevent ASCVD, focusing on significant LDL-C reduction and comprehensive lowering of apo B-containing lipoproteins. Emerging therapies, including ASO and RNA-based treatments, offer additional cardiovascular benefits.
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New Insights Into the Treatment of Hyperlipidemia: Pharmacological Updates and Emerging Treatments
Source : https://pubmed.ncbi.nlm.nih.gov/38919858/
Cardiovascular diseases are the leading causes of global mortality and morbidity. Hyperlipidemia is a significant risk factor for atherosclerosis and subsequent cardiovascular diseases. Hyperlipidemia is characterized by imbalances in blood...
Hyperlipidemia, influenced by genetics and lifestyle, is a key modifiable risk factor for cardiovascular diseases. Effective management involves lifestyle changes, traditional medications like statins, and emerging therapies such as PCSK9 inhibitors and inclisiran. Advances in genetic research and personalized medicine are enhancing...
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Osteoprotegerin mediates adipogenesis in obesity
Source : https://pubmed.ncbi.nlm.nih.gov/38906326/
OPG emerges as a key regulator in mediating adipogenesis during obesity development. Targeting OPG holds promise for the prevention and treatment of obesity, as evidenced by the efficacy of electroacupuncture...
OPG emerges as a key regulator in mediating adipogenesis during obesity development. Targeting OPG holds promise for the prevention and treatment of obesity, as evidenced by the efficacy of electroacupuncture treatment in modulating OPG levels and managing obesity-related outcomes.
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