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AHA Scientific Sessions 2025: Transformative advances in cardiovascular care

Dr. Joanna Chikwui, Chief of Cardiac Surgery at Cedars-Sinai and Chair of AHA Scientific Sessions, spotlighted significant breakthroughs across cardiology. Updates included novel therapies for hyperlipidemia, gene-editing tools for inherited cardiovascular risk, innovations in atrial fibrillation management, and compelling lifestyle findings—including a surprising inverse relationship between moderate coffee intake and AF incidence.

Dr. Heidi May, Epidemiologist at Intermountain Health, presented results from the Target-D randomized trial, which found that personalized vitamin D dosing after myocardial infarction significantly reduced the risk of recurrent heart attack. These findings underscore the importance of individualized supplementation strategies and signal a broader shift toward precision prevention and risk stratification in cardiovascular care.

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Use of intravenous lipid emulsions in drug-induced toxicities: a 2025 narrative review - PubMed

Use of intravenous lipid emulsions in drug-induced toxicities: a 2025 narrative review - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/41247632/

Intravenous lipid emulsions (ILE) were first proposed in 1998 as a treatment for bupivacaine-induced cardiac arrest. Since then, their use has expanded to include poisonings by various lipophilic drugs such...

ILEs treat lipophilic drug toxicities through lipid sink, shuttle, and cardiotonic mechanisms; benefits shown in select poisonings, but mortality impact, optimal dosing, and indications remain uncertain, requiring higher-quality evidence.

 

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56yr

Fun Fact! Statin-associated liver injury (SILI) is rare, with true liver damage seen in just 1 in 1,000 to 1 in 10,000 patients. Though 2.8–3.1% show elevated liver enzymes, most cases are mild and resolve after stopping treatment. Interestingly, statins may offer protection against chronic liver diseases like cirrhosis.

Could statins play a dual role in both managing cholesterol and protecting liver health?

NCCN Guidelines

Could statins play a dual role in both managing cholesterol and protecting liver health?

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Evaluating the impact of testosterone replacement therapy on carotid atherosclerosis: a systematic review and meta-analysis - PubMed

Evaluating the impact of testosterone replacement therapy on carotid atherosclerosis: a systematic review and meta-analysis - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/39183456/

Aim: This meta-analysis investigates the association between testosterone replacement therapy [TRT] and carotid artery atherosclerosis. Methods: 3 databases were searched for studies up to June 2023 per the PRISMA guidelines....

Testosterone therapy shows no association with carotid atherosclerosis or lipid/inflammatory markers, though it raises testosterone levels, suggesting safe use in hypogonadal men without increasing CIMT risk.

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