Clinical Competence, Communication Ability and Adherence to Choosing Wisely Recommendations for Lipid Reducing Drug Use in Older Adults
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662284
Although lipid-lowering drugs are not recommended for primary prevention in patients 75+, prevalence of use is high and there is unexplained variation in prescribing between physicians.
More clinically competent physicians were more likely to prescribe lipid-lowering drug for primary prevention but only to patients aged 75 years or older.
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LOGAN-CV: A Prospective Study of a Multifaceted Intervention Targeting United States Clinicians to Improve Guideline-Based Management of Lipid-Lowering Therapy
Source : https://link.springer.com/article/10.1007/s12325-023-02716-6
The 2018 American Heart Association (AHA)/American College of Cardiology (ACC)/Multisociety blood cholesterol guidelines recommend clinicians consider adding non-statin therapy for patients with very high-risk (VHR) atherosclerotic cardiovascular disease (ASCVD) and...
The clinician education modules developed can help in overcoming clinical inertia, support clinicians in providing guideline-based LLT, and enable patients to achieve recommended LDL-C levels.
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Coronary and Extra-Coronary Subclinical Atherosclerosis to Guide Lipid-Lowering Therapy
Source : https://link.springer.com/article/10.1007/s11883-023-01161-8
The most robust evidence for the use of CAC scoring is in select individuals, 40-75 years of age, at borderline to intermediate 10-year ASCVD risk.
Identification of coronary calcium in selected patients is the single best noninvasive imaging modality to identify future ASCVD risk and inform lipid-lowering therapy decision-making.
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Long-Term Mortality in Patients With Severe Hypercholesterolemia Phenotype From a Racial and Ethnically Diverse US Cohort
Source : https://pubmed.ncbi.nlm.nih.gov/37970713/
In a large, diverse cohort of US patients with the severe hypercholesterolemia phenotype, we identified several patient characteristics associated with increased 9-year all-cause mortality and observed a decrease in statin...
In a large, diverse cohort of US patients with the severe hypercholesterolemia phenotype, we identified several patient characteristics associated with increased 9-year all-cause mortality. A significant survival benefit was conferred by lipid-lowering therapy.
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Age-Dependent Association of Metabolic Dyslipidemia With Clinical Expression of Hypertrophic Cardiomyopathy
Source : https://pubmed.ncbi.nlm.nih.gov/37935337/
High triglyceride and low HDL-C levels are associated with a higher incidence of HCM, particularly in young individuals.
High triglyceride and low high-density lipoprotein cholesterol levels, the 2 dyslipidemia-related components of metabolic syndrome, are associated with a higher incidence of clinical HCM.
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