Triglycerides and Residual Atherosclerotic Risk

Source : https://www.jacc.org/doi/full/10.1016/j.jacc.2021.04.059

Effectiveness of Blood Lipid Management in Patients With Peripheral Artery Disease

Source : https://www.jacc.org/doi/abs/10.1016/j.jacc.2021.04.060

Circulating miRNAs miR-574-5p and miR-3135b are potential metabolic regulators for serum lipids and blood glucose in gestational diabetes mellitus

Source : https://doi.org/10.1080/09513590.2021.1908990

Abstract MicroRNAs (miRNAs) are potentially involved in the regulation of glucose and lipid metabolism. The aim of this study was to investigate potential miRNA regulators for serum lipids and blood...

Novel biomarker panel measuring endothelial injury identifies patients at risk of coronary artery syndrome and discordance with low-density lipoprotein cholesterol.

Source : https://europepmc.org/article/med/34138801

Background Individuals with no history of coronary artery disease can develop acute coronary syndrome (ACS), often in the absence of major risk factors including low-density lipoprotein cholesterol (LDL-C). We identified...

Is There Less Aggressive Lipid Management in PAD Patients? - American College of Cardiology

Source : https://www.acc.org/latest-in-cardiology/articles/2021/06/14/20/40/is-there-less-aggressive-lipid-management-in-pad-patients

For patients with peripheral artery disease (PAD), intensity of lipid-lowering therapy may be a "poor surrogate" for achieved LDL-cholesterol (LDL-C), as achieved LDL-C levels remain elevated for the majority of...

Atrial Fibrillation as a Possible Adverse Reaction to Evolocumab

Source : https://www.cureus.com/articles/61261-atrial-fibrillation-as-a-possible-adverse-reaction-to-evolocumab

Evolocumab is a recently FDA-approved proprotein convertase subtilisin/kexin type 9 inhibitor (PCSK9i) that reduces the risk of myocardial infarction, stroke, and coronary revascularization in individuals with established atherosclerotic cardiovascular disease....

Effect of More Intensive LDL-C–Lowering Therapy on Long-term Cardiovascular Outcomes in Early-Phase Acute Coronary Syndrome: A Systematic Review and Meta-analysis

Source : https://doi.org/10.1016/j.clinthera.2021.04.019

Management of Dyslipidemia in Patients with Diabetes - touchENDOCRINOLOGY

Source : https://doi.org/10.17925/USE.2011.07.01.40

In association with the global spread of abdominal adiposity, the worldwide prevalence of type 2 diabetes continues to increase.1 This is one of the pivotal factors underscoring the projection that...

ANKS1A genotype predicts cardiovascular events in patients with familial hypercholesterolemia

Source : https://doi.org/10.1016/j.jacl.2021.05.006

Founder effects facilitate the use of a genotyping‐based approach to molecular diagnosis in Swedish patients with familial hypercholesterolaemia

Source : https://onlinelibrary.wiley.com/doi/10.1111/joim.13287

P. Benedek , H. Jiao , J. Kere , M. Eriksson , B.

Polymorphisms of rs2483205 and rs562556 in the PCSK9 gene are associated with coronary artery disease and cardiovascular risk factors

Source : https://www.nature.com/articles/s41598-021-90975-0

PCSK9 plays a crucial role in lipid metabolism. This case-control study explored the associations of novel single nucleotide polymorphisms (SNPs) of the PCSK9 gene with coronary artery disease (CAD) (≥ 1...

The LDL-C/ApoB ratio predicts major cardiovascular events in patients with established atherosclerotic cardiovascular disease

Source : https://doi.org/10.1016/j.atherosclerosis.2021.05.010

Pcsk9 is associated with severity of coronary artery lesions in male patients with premature myocardial infarction

Source : https://lipidworld.biomedcentral.com/articles/10.1186/s12944-021-01478-w

Background Proprotein convertase subtilisin/kexin type 9 (Pcsk9) correlated with incidence and prognosis of coronary heart disease. However, it is unclear whether Pcsk9 contributed to coronary artery lesion severity in patients...

Effect of Moderately but Persistently Elevated Lipid Levels on Risks of Stroke and Myocardial Infarction in Young Korean Adults

Source : https://www.ahajournals.org/doi/full/10.1161/JAHA.120.020050?af=R

Effect of L-carnitine supplementation on lipid profile and apolipoproteins in children on hemodialysis: a randomized placebo-controlled clinical trial

Source : https://link.springer.com/article/10.1007/s00467-021-05080-1

Background Cardiovascular disease (CVD) is the leading cause of death in children with chronic kidney disease (CKD) and accounts for 40% of all deaths among pediatric patients with stage 5...

Safety and Efficacy of a Beverage Containing Lupine Protein Hydrolysates on the Immune, Oxidative and Lipid Status in Healthy Subjects: An Intervention Study (the Lupine‐1 Trial)

Source : https://onlinelibrary.wiley.com/doi/abs/10.1002/mnfr.202100139

Ivan Cruz-Chamorro , Guillermo Santos-Sánchez , María Carmen Millán-Linares , Alicia Martínez-López , Patricia Judith Lardone , Ignacio Bejarano , Juan Miguel Guerrero , Antonio Carrillo-Vico , Corresponding Author Instituto...

Clinical Significance of the Cardio-Ankle Vascular Index in Postmenopausal Women With Hypercholesterolemia | Hitsumoto | Journal of Clinical Medicine Research

Source : https://www.jocmr.org/index.php/JOCMR/article/view/4509

Abstract Background: The cardio-ankle vascular index (CAVI) is a physiological indicator of arterial elasticity. However, limited information regarding the clinical significance of the CAVI in patients with hypercholesterolemia is available....

Comparing impact of SGLT2 inhibitors and GLP-1 agonists on lipid profile among the patients with diabetes mellitus Type 2. Results of a prospective 18-week observational study

Source : https://www.endocrine-abstracts.org/ea/0073/ea0073aep305

1Tbilisi Heart and Vascular Clinic, Tblisi, Gerogia; 2National institute of Endocrinology, Tblisi, Georgia; 3Clinic 'ENMEDIC', Tblisi, Georgia; 4 'Family Doctor', Tblisi, Georgia Background In Georgia, significantly huge number of patients...

Structure–activity relationship and biological evaluation of berberine derivatives as PCSK9 down-regulating agents

Source : https://doi.org/10.1016/j.bioorg.2021.104994

PRIME PubMed | The combination of sesamol and clofibric acid moieties leads to a novel potent hypolipidemic agent with antioxidant, anti-inflammatory and hepatoprotective activity

Source : https://www.unboundmedicine.com/medline/citation/34015506/The_combination_of_sesamol_and_clofibric_acid_moieties_leads_to_a_novel_potent_hypolipidemic_agent_with_antioxidant

Oxidative stress and inflammation have been considered the main factors in the liver injury of clofibrate (CF). To obtain a novel antihyperlipidemic agent with antioxidant, anti-inflammation and hepatoprotection, the combination...