Bempedoic Acid in the Treatment of Patients with Dyslipidemias and Statin Intolerance
Source : https://link.springer.com/article/10.1007/s10557-020-07139-x
An elevated plasma low-density lipoprotein cholesterol (LDL-C) level is a well-established atherosclerotic cardiovascular disease (ACSVD) risk factor. Randomized studies with statins (alone or in combination with other lipid-lowering drugs) have...
Elevated Lipids are Associated with Reduced Regional Brain Structure in Youth with Bipolar Disorder.
Source : https://europepmc.org/article/med/33492669
Objective Abnormal blood lipid levels are common in bipolar disorder (BD) and correlate with mood symptoms and neurocognition. However, studies have not examined the lipid-brain structure association in BD or...
Echolucency of carotid plaque is useful for selecting high-risk patients with chronic coronary artery disease who benefit from intensive lipid-lowering therapy - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/33500186/
1 Department of Internal Medicine II, University of Yamanashi, Faculty of Medicine, Chuo, Yamanashi, Japan. 2 Department of Internal Medicine II, University of Yamanashi, Faculty of Medicine, Chuo, Yamanashi, Japan....
Performance of Methods to Estimate Low-Density Lipoprotein Cholesterol in Women with and without HIV infection.
Source : https://europepmc.org/article/med/33470728
Background Low-density lipoprotein cholesterol (LDL-C) is estimated from total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) using predefined equations which assume fixed or varying relationships between these parameters...
Reaching LDL-C Targets in Patients with Moderate, High, and Very High Risk for Cardiovascular Disease After Bariatric Surgery According to Different Guidelines
Source : https://link.springer.com/article/10.1007/s11695-021-05221-3
Background Cardiovascular disease (CVD) is highly prevalent in obese patients and is the leading cause of death. High levels of plasma low-density lipoprotein cholesterol (LDL-C) are associated with higher coronary...
Obesity and Prediabetes are Jointly Associated with Lipid Abnormalitie | DMSO
Mohammad Almari, 1, * Anwar Mohammad, 2, * Jehad Abubaker, 2 Ali H Ziyab 3 1Department of Health Policy and Management, Faculty of Public Health, Kuwait University, Safat, Kuwait; 2Department...
The correlation between lipoprotein(a) and coronary atherosclerotic lesion is stronger than LDL-C, when LDL-C is less than 104 mg/dL
Source : https://bmccardiovascdisord.biomedcentral.com/articles/10.1186/s12872-021-01861-6
Background Lp(a) and LDL-C are both risk factors of atherosclerotic cardiovascular disease (ASCVD). But there was a contradiction point in LDL-C and Lp(a) control. The appropriate level of LDL-C and...
Effects of Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 Supplementation on Nutritional and Metabolic Parameters in the Early Postoperative Period after Roux-en-Y Gastric Bypass: a Randomized, Double-Blind, Placebo-Controlled Trial
Source : https://link.springer.com/article/10.1007/s11695-021-05222-2
Abstract Studies have suggested that Roux-en-Y gastric bypass (RYGB) causes changes in the intestinal microbiota composition and function due to anatomical and physiological modifications. The role of probiotic supplementation after...
A polygenic biomarker to identify patients with severe hypercholesterolemia of polygenic origin - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/32307928/
doi: 10.1002/mgg3.1248. 1 Department of Life Sciences, Centre for Integrative Systems Biology and Bioinformatics, Imperial College London, London, United Kingdom. 2 Department of Medicine, Imperial College London, London, United Kingdom....
Improved lipid target level attainment in patients with peripheral artery disease - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/33430734/
It appears that there is more awareness and improvement of previously documented undertreatment of LDL-C levels in symptomatic PAD patients. Although statin treatment is initiated in the majority of patients,...
Clinical Efficacy and Safety of Alirocumab after Acute Coronary Syndrome According to Achieved Level of Low-Density Lipoprotein Cholesterol: A Propensity Score-Matched Analysis of the ODYSSEY OUTCOMES Trial - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/33438437/
doi: 10.1161/CIRCULATIONAHA.120.049447. Online ahead of print. 1 Division of Cardiology, University of Colorado School of Medicine, Aurora, CO. 2 Université de Paris, Assistance Publique-Hôpitaux de Paris, Hôpital Bichat, INSERM U1148,...
Association of lipid profile in migraine and non- migraine patients: an observational study
Source : https://www.ijhcr.com/index.php/ijhcr/article/view/516
Anchal Bana Post Graduate Student, Department Of Ophthalmology, Muzaffarnagar Medical College, Muzaffarnagar, U.P, India Suman Bhartiya Professor and Head, Department Of Ophthalmology, Muzaffarnagar Medical College, Muzaffarnagar, U.P , India. Prachi...
The Association Between Statin Use and Outcomes in Patients Initiating Androgen Deprivation Therapy.
Studies have conflicting results regarding the association between statin use and biochemical recurrence for prostate cancer (PCa). A limited number of studies examining statins in advanced stages report positive results,...
Can Coronary Artery Calcium Scores Help to Personalize Risk Assessment and Tailor Treatment in Familial Hypercholesterolemia? - American College of Cardiology
Background Heterozygous familial hypercholesterolemia (HeFH) affects approximately one in 250 Americans, making it one of the most common genetic conditions associated with premature atherosclerotic cardiovascular disease (ASCVD).
Detection of Asymptomatic Carotid Artery Stenosis in High-Risk Individuals of Stroke Using a Machine-Learning Algorithm - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/33413745/
Objective Asymptomatic carotid stenosis (ACS) is closely associated to the incidence of severe cerebrovascular diseases. Early identifying the individuals with ACS and its associated risk factors could be beneficial for...
LDL-cholesterol change and goal attainment following statin intensity titration among Asians in primary care: a retrospective cohort study
Source : https://link.springer.com/article/10.1186/s12944-020-01427-z
Clinical trials have demonstrated that either initiating or up-titrating a statin dose substantially reduce Low-Density Lipoprotein-Cholesterol (LDL-C) levels. However, statin adherence in actual practice tends to be suboptimal, leading to...
Selenium levels and glutathione peroxidase activity in patients with ataxia-telangiectasia: association with oxidative stress and lipid status biomarkers
Source : https://europepmc.org/article/ppr/ppr262231
Introduction: Ataxia-Telangiectasia (A-T) is a multi-system disorder that may be associated with endocrine changes, oxidative stress in addition to inflammation. Studies suggest that selenium is a trace element related to...