Inclisiran Response in a Patient With Familial Hypercholesterolemia After Suboptimal Response to Evolocumab. - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/42397340
A patient with familial hypercholesterolemia responded well to inclisiran after an inadequate response to evolocumab, as detailed in this case report.
Inclisiran showed efficacy in reducing LDL cholesterol in a patient with familial hypercholesterolemia (Afrikaner-2 variant) after suboptimal response to evolocumab.
Biologics for cardiovascular diseases: from bench to bedside. - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/42366210
Explore the role of biologics, including gene therapies and lipid modulation, in managing cardiovascular diseases by addressing pathophysiological mechanisms.
Biologics offer potential for disease modification in cardiovascular medicine, focusing on cardiac regeneration, reverse remodeling, genetic correction, vascular modulation, and lipid metabolism.
National Heart Center/Saudi Heart Association 2025 Guidelines for Cardiovascular Diseases Prevention and Risk Assessment. - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41628971
Explore the 2025 guidelines for cardiovascular disease prevention in Saudi Arabia, highlighting primary risk assessment and secondary comorbidity management.
The 2025 guidelines emphasize tailored prevention strategies for cardiovascular diseases in Saudi Arabia, focusing on primary prevention through risk assessment and secondary prevention with comorbidity management.
In very high-risk patients above LDL-C goal on maximally tolerated statin, what guides your next step?
Primary and Secondary Prevention of Ischemic Stroke in Elderly Patients with Cardiovascular Disease: The Role of Frailty and Care Pathways. - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41745720
Explore how frailty-informed strategies, multidisciplinary care, and sex- and age-related factors impact ischemic stroke prevention in elderly with cardiovascular diseases. Focus ...
Frailty indices aid individualized stroke prevention in elderly with cardiovascular disease, emphasizing multidisciplinary care, antithrombotic strategies, and considering sex- and age-related treatment factors.