Lipid dysregulation and delirium in older adults: A review of the current evidence and future directions - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40086765/
Delirium is a complex medical condition marked by acute episodes of cognitive dysfunction and behavioral disturbances, with a multifaceted etiology and challenging management across various clinical settings. Older adults, particularly...
Lipid dysregulation may contribute to delirium in older adults, particularly postoperatively, prompting interest in lipid-targeted therapies. Further research into age-related neurolipid changes is essential for novel interventions.
Omega-3 Polyunsaturated Fatty Acids in Depression - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39201362/
Omega-3 polyunsaturated fatty acids have received considerable attention in the field of mental health, in particular regarding the treatment of depression. This review presents an overview of current research on...
Omega-3 fatty acids, especially EPA and DHA, show potential antidepressant effects, but inconsistent clinical results highlight the need for further research to establish standardized depression treatment guidelines.
Acetaminophen for Prevention and Treatment of Organ Dysfunction in Critically Ill Patients With Sepsis: The ASTER Randomized Clinical Trial - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38762798/
ClinicalTrials.gov Identifier: NCT04291508.
In this randomized trial, IV acetaminophen was safe in sepsis patients but did not significantly increase days alive and free of organ support; some secondary organ function improvements were noted.
Comprehensive Review of Lipid Management in Chronic Kidney Disease and Hemodialysis Patients: Conventional Approaches, and Challenges for Cardiovascular Risk Reduction - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39860649/
Background/Objectives : Lipid disorders are very prevalent in patients with chronic kidney disease (CKD) and end-stage kidney disease (ESKD), leading to heightened cardiovascular risk. This review examines the effectiveness of...
Lipid-lowering therapies in CKD/ESRD show limited cardiovascular benefits, especially in dialysis patients. While statins and PCSK9 inhibitors offer potential, further research is needed to optimize treatment strategies for these populations.
Clinical practice guideline for the management of lipids in adults with diabetic kidney disease: abbreviated summary of the Joint Association of British Clinical Diabetologists and UK Kidney Association (ABCD-UKKA) Guideline 2024 - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38971750/
The contribution of chronic kidney disease (CKD) towards the risk of developing cardiovascular disease (CVD) is magnified with co-existing type 1 or type 2 diabetes. Lipids are a modifiable risk...
This guideline provides practical recommendations on lipid management to reduce cardiovascular risk in adults with diabetic kidney disease, aiming to improve outcomes through multidisciplinary care for CKD and diabetes.