New insights in lipid metabolism: potential therapeutic targets for the treatment of Alzheimer's disease - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39323915/
Alzheimer's disease (AD) is increasingly recognized as being intertwined with the dysregulation of lipid metabolism. Lipids are a significant class of nutrients vital to all organisms, playing crucial roles in...
Alzheimer's disease is linked to lipid metabolism dysregulation, with cholesterol, sphingolipids, and fatty acids influencing key pathologies. Targeting lipid metabolism offers potential therapeutic strategies, including diets, statins, and novel compounds.
2024 KSoLA consensus on secondary dyslipidemia - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39252486/
Elevated blood cholesterol and triglyceride levels induced by secondary causes are frequently observed. The identification and appropriate handling of these causes are essential for secondary dyslipidemia treatment. Major secondary causes...
Secondary dyslipidemia necessitates identifying and addressing underlying causes before initiating lipid-lowering therapy, focusing on dietary factors, metabolic diseases, and medication side effects.
Practical solutions for implementation of blood cholesterol guidelines in clinical practice - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37634754/
Underutilization of lipid-lowering therapy (LLT) and failure to attain guideline-recommended low-density lipoprotein cholesterol (LDL-C) goals are important quality gaps in cardiovascular risk optimization, especially among patients with atherosclerotic cardiovascular disease...
Many patients with atherosclerotic cardiovascular disease (ASCVD) do not achieve recommended LDL-C levels due to underutilization of lipid-lowering therapy; multifaceted interventions are needed for optimal management.
Insights into the interplay between gut microbiota and lipid metabolism in the obesity management of canines and felines - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39118186/
Obesity is a prevalent chronic disease that has significant negative impacts on humans and our companion animals, including dogs and cats. Obesity occurs with multiple comorbidities, such as diabetes, hypertension,...
The review explores lipid metabolism's role in obesity-related disorders in dogs and cats, emphasizing gut microbiota and management strategies including nutritional interventions for effective obesity treatment.
Medications for Lipid Control: Statins vs Newer Drugs - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39111897/
In the primary and secondary prevention of atherosclerotic cardiovascular disease (ASCVD), statins are the primary pharmacologic intervention for ASCVD risk reduction. Statins have proven efficacy and safety in reducing cardiovascular...
Statins are key for ASCVD prevention, with proven efficacy. Alternative therapies like ezetimibe and PCSK9 inhibitors, along with emerging treatments, enhance lipid management and cardiovascular outcomes.