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The gut microbiota functions like a vital organ, essential for human health. By analyzing metagenomic data from dietary interventions in type 2 diabetes and multiple diseases, the researchers in the linked study identified stable gut microbial relationships. The study model reveals two competing guilds: one for fiber fermentation and butyrate production, and another linked to virulence and antibiotic resistance.

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American Heart Association Scientific Sessions

The American Heart Association (AHA) will be hosting its annual scientific sessions at the McCormick Place Convention Center in Chicago from Nov. 16 to 18, 2024. This conference will focus on the latest innovations for scientists, clinicians, researchers, and other health care professionals interested in cardiovascular disease.

We will be covering the event for you, so stay tuned for reports with highlights and a wrap-up of the conference. Click above to access some of the highlights that caught our attention.

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Management of triglycerides, non-high density lipoprotein cholesterol and high density lipoprotein cholesterol - PubMed

Management of triglycerides, non-high density lipoprotein cholesterol and high density lipoprotein cholesterol - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/37979723/

Dyslipidaemia characterised by elevated total cholesterol/LDL-C, triglyceride or both or decreased HDL-C is an important risk factor for the development of ASCVD. Atherogenic dyslipidaemia characterised by high TG, low HDL-C...

Dyslipidaemia increases ASCVD risk, particularly in Asian Indians. Management includes lifestyle changes and pharmacotherapy for severe cases. Non-HDL-C is a better ASCVD risk marker than HDL-C, which lacks proven causality.

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Role of PCSK9 inhibitors in the management of dyslipidaemia - PubMed

Role of PCSK9 inhibitors in the management of dyslipidaemia - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38195006/

Proprotein convertase subtilisin kexin9 (PCSK9) inhibitors are novel agents that lower LDL cholesterol and reduce cardio-vascular event rate. Being expensive, these agents are reserved for those with high risk or...

PCSK9 inhibitors lower LDL cholesterol and cardiovascular event rates, reserved for high-risk patients with inadequate responses to statins and ezetimibe or those intolerant to statins due to high cost.

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Evolution of More Aggressive LDL-Cholesterol Targets and Therapies for Cardiovascular Disease Prevention - PubMed

Evolution of More Aggressive LDL-Cholesterol Targets and Therapies for Cardiovascular Disease Prevention - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38068483/

Over the last half-century, discussions on the exact targets for low-density lipoprotein cholesterol (LDL-C) reduction have evolved towards a more aggressive approach with lower LDL-C targets, particularly for high-risk patients...

This paper reviews the evolution of LDL-C targets in lipid management, highlighting the efficacy of statins and newer therapies in reducing ASCVD risk and advocating for lower LDL-C goals.

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