Exploring the clinical effectiveness of glucagon-like peptide-1 receptor agonists in managing cardiovascular complications: an updated comprehensive review and future directives
Source : https://pubmed.ncbi.nlm.nih.gov/39359798/
The possible cardiovascular advantages of glucagon-like peptide-1 receptor agonists (GLP-1RAs), a class of drugs predominantly used to treat type 2 diabetes (T2D), have garnered increasing attention in recent years. Clinical...
GLP-1 receptor agonists demonstrate promise in managing type 2 diabetes and reducing cardiovascular risk, but further research is needed to optimize treatment regimens and enhance long-term patient outcomes.
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Diet to Stop Hypertension: Should Fats be Included? - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38713264/
Since reducing salt consumption is an established recommendation only corollary dietary advice is subject to the current review. Population studies that have included reliable evaluation of fat intake have indicated...
Recent data suggest that reducing salt, incorporating marine oils, and following specific dietary patterns (e.g., plant-based, dairy, fat-adjusted) may help lower blood pressure, especially with weight reduction.
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New insights in lipid metabolism: potential therapeutic targets for the treatment of Alzheimer's disease - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39323915/
Alzheimer's disease (AD) is increasingly recognized as being intertwined with the dysregulation of lipid metabolism. Lipids are a significant class of nutrients vital to all organisms, playing crucial roles in...
Alzheimer's disease is linked to lipid metabolism dysregulation, with cholesterol, sphingolipids, and fatty acids influencing key pathologies. Targeting lipid metabolism offers potential therapeutic strategies, including diets, statins, and novel compounds.
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2024 KSoLA consensus on secondary dyslipidemia - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39252486/
Elevated blood cholesterol and triglyceride levels induced by secondary causes are frequently observed. The identification and appropriate handling of these causes are essential for secondary dyslipidemia treatment. Major secondary causes...
Secondary dyslipidemia necessitates identifying and addressing underlying causes before initiating lipid-lowering therapy, focusing on dietary factors, metabolic diseases, and medication side effects.
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Practical solutions for implementation of blood cholesterol guidelines in clinical practice - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37634754/
Underutilization of lipid-lowering therapy (LLT) and failure to attain guideline-recommended low-density lipoprotein cholesterol (LDL-C) goals are important quality gaps in cardiovascular risk optimization, especially among patients with atherosclerotic cardiovascular disease...
Many patients with atherosclerotic cardiovascular disease (ASCVD) do not achieve recommended LDL-C levels due to underutilization of lipid-lowering therapy; multifaceted interventions are needed for optimal management.
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