Dapagliflozin added to metformin reduces perirenal fat layer in type 2 diabetic patients with obesity
Source : https://pubmed.ncbi.nlm.nih.gov/38734755/
Sodium-glucose co-transporters type 2 inhibitors (SLGT2i) are highly effective in controlling type 2 diabetes, but reported beneficial cardiovascular effects suggest broader actions on insulin resistance. Weight loss may be initially...
Both metformin and dapagliflozin effectively reduce abdominal fat in type 2 diabetes patients, with combined treatment particularly targeting perirenal fat, suggesting enhanced cardiovascular benefits of dapagliflozin.
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Inositol for Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis to Inform the 2023 Update of the International Evidence-based PCOS Guidelines
Source : https://pubmed.ncbi.nlm.nih.gov/38163998/
The evidence supporting the use of inositol in the management of PCOS is limited and inconclusive. Clinicians and their patients should consider the uncertainty of the evidence together with individual...
The evidence supporting the use of inositol in the management of PCOS is limited and inconclusive. Clinicians and their patients should consider the uncertainty of the evidence together with individual values and preferences when engaging in shared decision-making regarding the use of inositol for PCOS.
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Lipid Association of India 2023 update on cardiovascular risk assessment and lipid management in Indian patients: Consensus statement IV
Source : https://pubmed.ncbi.nlm.nih.gov/38485619/
This document presents the updated risk stratification and treatment algorithm and describes the rationale for each modification. The intent of these updated recommendations is to modernize management of dyslipidemia in...
Updated risk stratification and treatment algorithm and describes the rationale for each modification. The intent of these updated recommendations is to modernize management of dyslipidemia in Indian patients with the goal of reducing the epidemic of ASCVD among Indians in Asia and worldwide.
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Unique features of dyslipidemia in women across a lifetime and a tailored approach to management
Source : https://pubmed.ncbi.nlm.nih.gov/38634109/
Pathophysiology of dyslipidemia varies between men and women and across a woman's lifetime. While increased lipid levels or lipid imbalances are more common in postmenopausal women over age 50, conditions...
Managing dyslipidemia in women involves early screening, lifestyle changes, and pharmacotherapy tailored to achieve guideline-directed LDL-C levels, addressing risks across different life stages and conditions like PCOS and FH.
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Lipid-based eye drop formulations for the management of evaporative dry eyes
Source : https://pubmed.ncbi.nlm.nih.gov/38523013/
Dry eye disease is a progressive prevalent ocular surface disorder that arises from various factors and is characterized by insufficient quality and/or quantity of tears. The underlying pathophysiology is intricate...
Lipid-based eye drops show potential for treating evaporative dry eyes, but further placebo-controlled trials and innovations are needed to optimize formulations and effectiveness in replicating natural tear lipids.
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