Prevalence of familial hypercholesterolemia and its association with coronary artery disease: A Chinese cohort study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37305106/
The prevalence of FH was estimated to be 0.19% in the participants, and it was associated with an elevated risk of incident CAD. Our study suggests that early screening of...
Conclusions: The prevalence of FH was estimated to be 0.19% in the participants, and it was associated with an elevated risk of incident CAD. Our study suggests that early screening of FH has certain public health significance for the prevention of CAD.
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SARS-CoV-2 reinfection: Adding insult to dysfunctional endothelium in patients with atherosclerotic cardiovascular disease
Source : https://www.sciencedirect.com/science/article/pii/S266708952300010X?via=ihub
In this short narrative review, we aim at defining the pathophysiological role endothelial dysfunction in the observed COVID-19-associated rise in ris...
Conclusion: Considering weakened protection against the cardiovascular risk-enhancing reinfections with emerging new subvariants of SARS-CoV-2, treatment of COVID-19 patients with statins during the illness and thereafter is recommended, partly because the statins tend to reduce endothelial dysfunction.
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Differences in treatment strategies for LDL-cholesterol reduction in a university lipid clinic vs. standard care apart from the use of PCSK9 inhibitors - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37271601/
Treatment in a lipid clinic leads to a superior LDL-C goal achievement in very high-risk CVD patients as compared to standard care with the highest reduction under LLT with high-intensity...
Conclusion: Treatment in a lipid clinic leads to a superior LDL-C goal achievement in very high-risk CVD patients as compared to standard care with the highest reduction under LLT with high-intensity statins and ezetimibe. Referral algorithms have to be established for high-risk patients.
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Lipid Management Connect2yrKey Points • Source: Journal of Clinical Lipidology • Conclusions/Relevance: “Lipid-lowering therapy (LLT) in patients with cardiovascular disease (CVD) is insufficient despite clear guideline recommendations. Lipid clinics have specialized in patients with dyslipidemia, but Show More
Lipoprotein Particle Profiles Associated with Telomere Length and Telomerase Complex Components - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37299586/
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Conclusions/Relevance: Our results suggest that the lipoprotein profiles are associated with telomere length, TERT, and WRAP53 expression and should be considered when assessing the risk of chronic diseases.
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Analysis of the evolocumab (Repatha®) patient support program for patients with cardiovascular disease in Colombia
Source : https://www.sciencedirect.com/science/article/abs/pii/S021491682300044X?via=ihub
Available online 3 June 2023 Author links open overlay panel, Mariana Pineda-Posada b , , , Show more Las enfermedades cardiovasculares son la principal causa de muerte a nivel mundial.
Conclusion: This is the first real-life study describing patient characteristics, compliance and continuity of treatment for dyslipidemia in a patient support program in Colombia. The overall adherence found was higher than 70%; similar to findings reported in other real-life studies with iPCSK9. However, the reasons for low compliance were...
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