Founder effects facilitate the use of a genotyping‐based approach to molecular diagnosis in Swedish patients with familial hypercholesterolaemia

Source : https://onlinelibrary.wiley.com/doi/10.1111/joim.13287

P. Benedek , H. Jiao , J. Kere , M. Eriksson , B.

Polymorphisms of rs2483205 and rs562556 in the PCSK9 gene are associated with coronary artery disease and cardiovascular risk factors

Source : https://www.nature.com/articles/s41598-021-90975-0

PCSK9 plays a crucial role in lipid metabolism. This case-control study explored the associations of novel single nucleotide polymorphisms (SNPs) of the PCSK9 gene with coronary artery disease (CAD) (≥ 1...

The LDL-C/ApoB ratio predicts major cardiovascular events in patients with established atherosclerotic cardiovascular disease

Source : https://doi.org/10.1016/j.atherosclerosis.2021.05.010

Pcsk9 is associated with severity of coronary artery lesions in male patients with premature myocardial infarction

Source : https://lipidworld.biomedcentral.com/articles/10.1186/s12944-021-01478-w

Background Proprotein convertase subtilisin/kexin type 9 (Pcsk9) correlated with incidence and prognosis of coronary heart disease. However, it is unclear whether Pcsk9 contributed to coronary artery lesion severity in patients...

Effect of Moderately but Persistently Elevated Lipid Levels on Risks of Stroke and Myocardial Infarction in Young Korean Adults

Source : https://www.ahajournals.org/doi/full/10.1161/JAHA.120.020050?af=R