Thirty percent of children and young adults with familial hypercholesterolemia treated with statins have adherence issues

Source : https://doi.org/10.1016/j.ajpc.2021.100180

Genome-wide association study of fish oil supplementation on lipid traits in 81,246 individuals reveals new gene-diet interaction loci

Source : https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1009431

Author summary We utilized the unprecedentedly large genotype and phenotype dataset in the UK Biobank to perform a genome-wide association study (GWAS) which accounts for the interplay between genotype and...

Clinical Importance of the LDL-C/Apolipoprotein B Ratio for Neointimal Formation after Everolimus-Eluting Stent Implantations - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/33746158/

A low LDL-C/Apo B ratio was found to be strongly associated with neointimal proliferation and neointimal instability evidenced chronically by OCT and CAS. An LDL-C/Apo B ≤ 1.2 will be...

Similar major cardiovascular outcomes between pure statin and ezetimibe-statin in comparable intensity for type 2 diabetes with extremely atherosclerotic risks

Source : https://www.nature.com/articles/s41598-021-86090-9

Atorvastatin 40 mg (ATOR 40) and ezetimibe 10 mg/simvastatin 20 mg (EZ-SIM 20) have similar reductions of low-density lipoprotein cholesterol (LDL-C) but cardiovascular (CV) outcomes between these two therapies are...

Application of the Sampson equation to estimate LDL-C in children: comparison with LDL direct measurement and Friedewald equation in the BLIP Study

Source : https://doi.org/10.1016/j.numecd.2021.02.034