10mo
Discussion Prompt: How have payor criteria shaped your timing of anti‑CGRP MAbs, and patient outcomes?
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10mo
Acetaminophen for Prevention and Treatment of Organ Dysfunction in Critically Ill Patients With Sepsis: The ASTER Randomized Clinical Trial - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38762798/
ClinicalTrials.gov Identifier: NCT04291508.
In this randomized trial, IV acetaminophen was safe in sepsis patients but did not significantly increase days alive and free of organ support; some secondary organ function improvements were noted.
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10mo
Comprehensive Review of Lipid Management in Chronic Kidney Disease and Hemodialysis Patients: Conventional Approaches, and Challenges for Cardiovascular Risk Reduction - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39860649/
Background/Objectives : Lipid disorders are very prevalent in patients with chronic kidney disease (CKD) and end-stage kidney disease (ESKD), leading to heightened cardiovascular risk. This review examines the effectiveness of...
Lipid-lowering therapies in CKD/ESRD show limited cardiovascular benefits, especially in dialysis patients. While statins and PCSK9 inhibitors offer potential, further research is needed to optimize treatment strategies for these populations.
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10mo
Clinical practice guideline for the management of lipids in adults with diabetic kidney disease: abbreviated summary of the Joint Association of British Clinical Diabetologists and UK Kidney Association (ABCD-UKKA) Guideline 2024 - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38971750/
The contribution of chronic kidney disease (CKD) towards the risk of developing cardiovascular disease (CVD) is magnified with co-existing type 1 or type 2 diabetes. Lipids are a modifiable risk...
This guideline provides practical recommendations on lipid management to reduce cardiovascular risk in adults with diabetic kidney disease, aiming to improve outcomes through multidisciplinary care for CKD and diabetes.
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11mo
Effects of Cocoa Consumption on Cardiometabolic Risk Markers: Meta-Analysis of Randomized Controlled Trials - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38931273/
The consumption of cocoa showed protective effects on major cardiometabolic risk markers that have a clinical impact in terms of cardiovascular risk reduction.
Cocoa consumption modestly improves LDL-c, total cholesterol, fasting glucose, and blood pressure in adults, but shows no impact on weight, BMI, waist circumference, triglycerides, HDL-c, or HbA1c.
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