Practical solutions for implementation of blood cholesterol guidelines in clinical practice - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37634754/
Underutilization of lipid-lowering therapy (LLT) and failure to attain guideline-recommended low-density lipoprotein cholesterol (LDL-C) goals are important quality gaps in cardiovascular risk optimization, especially among patients with atherosclerotic cardiovascular disease...
Many patients with atherosclerotic cardiovascular disease (ASCVD) do not achieve recommended LDL-C levels due to underutilization of lipid-lowering therapy; multifaceted interventions are needed for optimal management.
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Insights into the interplay between gut microbiota and lipid metabolism in the obesity management of canines and felines - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39118186/
Obesity is a prevalent chronic disease that has significant negative impacts on humans and our companion animals, including dogs and cats. Obesity occurs with multiple comorbidities, such as diabetes, hypertension,...
The review explores lipid metabolism's role in obesity-related disorders in dogs and cats, emphasizing gut microbiota and management strategies including nutritional interventions for effective obesity treatment.
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Medications for Lipid Control: Statins vs Newer Drugs - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39111897/
In the primary and secondary prevention of atherosclerotic cardiovascular disease (ASCVD), statins are the primary pharmacologic intervention for ASCVD risk reduction. Statins have proven efficacy and safety in reducing cardiovascular...
Statins are key for ASCVD prevention, with proven efficacy. Alternative therapies like ezetimibe and PCSK9 inhibitors, along with emerging treatments, enhance lipid management and cardiovascular outcomes.
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PCSK9 inhibition: from effectiveness to cost-effectiveness
Source : https://pubmed.ncbi.nlm.nih.gov/38988669/
Dyslipidaemia is a complex disorder characterised by abnormal lipid levels in the blood, including cholesterol and triglycerides, and plays an important role in the development of atherosclerotic cardiovascular disease. Most...
PCSK9 inhibitors are effective in lowering LDL cholesterol and offer significant benefits for high-risk patients. Despite high costs and mixed cost-effectiveness results, they remain a valuable treatment option.
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Lipid levels and risk of acute pancreatitis using bidirectional Mendelian randomization
Source : https://pubmed.ncbi.nlm.nih.gov/38491158/
Previous studies found lipid levels, especially triglycerides (TG), are associated with acute pancreatitis, but their causalities and bi-directions were not fully examined. We determined whether abnormal levels of TG, high-density...
Higher triglycerides are a risk factor for acute pancreatitis, while lower HDL-C is both a risk factor and a consequence. HDL-C modulation may aid in prevention and treatment.
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