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Genetically predicted lipids mediate the association between intrahepatic cholestasis of pregnancy and cardiovascular disease

Genetically predicted lipids mediate the association between intrahepatic cholestasis of pregnancy and cardiovascular disease

Source : https://pubmed.ncbi.nlm.nih.gov/38745758/

The results underscore the genetic predisposition of ICP to elevate CVD risk and the critical mediating role of lipid levels, emphasizing the need for vigilant lipid monitoring and early intervention...

The results underscore the genetic predisposition of ICP to elevate CVD risk and the critical mediating role of lipid levels, emphasizing the need for vigilant lipid monitoring and early intervention in individuals with ICP.

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Individual Variation in the Distribution of Apolipoprotein B Levels Across the Spectrum of LDL-C or Non–HDL-C Levels

Source : https://jamanetwork.com/journals/jamacardiology/article-abstract/2820073

This study suggests that because there is a substantial range of values of apoB for any value of LDL-C or non–HDL-C, restricting testing of apoB to those with metabolic risk factors will miss a substantial minority of individuals with discordantly elevated levels of apoB relative to LDL-C or non–HDL-C.

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Revolutionizing Lipid Management: Insights from Daniel Soffer, MD

Join Daniel Soffer, MD, a leading internist and lipid specialist and the immediate past president of the National Lipid Association, as he shares groundbreaking advancements in lipid management from the recent NLA meeting. Discover the importance of measuring patient responses, the benefits of combination therapies, and the latest in drug development for tackling lipid disorders.

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Use of lipid ratios to predict vascular target organ damage in youth

Use of lipid ratios to predict vascular target organ damage in youth

Source : https://pubmed.ncbi.nlm.nih.gov/38462388/

Arterial stiffness is increased in youth with high lipid ratios with TG/HDL-C being the most consistent marker of vascular changes. These data suggest that identification of high TG/HDL-C in these...

Arterial stiffness is increased in youth with high lipid ratios with TG/HDL-C being the most consistent marker of vascular changes. These data suggest that identification of high TG/HDL-C in these individuals may lead to earlier intervention to prevent atherosclerotic cardiovascular disease.

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Lipids as potential mediators linking body mass index to diabetes: evidence from a mediation analysis based on the NAGALA cohort

Lipids as potential mediators linking body mass index to diabetes: evidence from a mediation analysis based on the NAGALA cohort

Source : https://pubmed.ncbi.nlm.nih.gov/38730299/

Our fresh findings suggested that lipid parameters partially mediated the association of BMI with diabetes risk; this result indicated that in the context of diabetes risk screening and disease management,...

Our fresh findings suggested that lipid parameters partially mediated the association of BMI with diabetes risk; this result indicated that in the context of diabetes risk screening and disease management, it is important to not only monitor BMI but also pay attention to lipid parameters, particularly HDL-C and HDL-C-related lipid ratio...

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