Remnant Cholesterol as a New Lipid-Lowering Target to Reduce Cardiovascular Events
Current and novel therapeutic approaches to target remnant cholesterol are discussed. Recent findings A recent Mendelian randomization study of over 12 000 000 single-nucleotide polymorphisms associated with high levels of remnant cholesterol,...
A recent Mendelian randomization study of >12 million single-nucleotide polymorphisms associated with high levels of remnant cholesterol demonstrated a genetic association between remnant cholesterol and adverse cardiovascular events among nearly 1 million participants.
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Effect of Household Income on Cardiovascular Diseases, Cardiovascular Biomarkers, and Socioeconomic Factors
Source : https://pubmed.ncbi.nlm.nih.gov/38350757
Higher household income is causally associated with better socioeconomic factors and improved cardiovascular biomarkers, which translates into a reduced prevalence of cardiovascular diseases. Policies to improve income equality may result...
Higher household income is causally associated with better socioeconomic factors and improved CV biomarkers, which translates into a reduced prevalence of CVD.
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Association Between Serum Triglyceride Level and Severity of Acute Biliary Pancreatitis
Source : https://pubmed.ncbi.nlm.nih.gov/38350790/
Elevated serum TG levels were independently associated with more severe ABP. The incidence of POF, APFC, and ANC in ABP patients increased with the increase of TG levels, with a...
ABP is the most common type of AP, with an abrupt onset, rapid progression, and a tendency to develop SIRS and multiple organ dysfunction syndrome.
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Association Between Lipid Profile in Early Pregnancy and the Risk of Congenital Heart Disease in Offspring: a Prospective Cohort Study
Source : https://www.nature.com/articles/s41598-024-53876-6
This study aimed to investigate the association of lipid profile in early pregnancy and the risk of congenital heart disease (CHD) in offspring. This study was a prospective cohort design...
The study discovered that higher TG, LDL, and Apo B levels in early pregnancy were associated with an increased risk of CHD in offspring.
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Lysophosphatidic Acid-Mediated Inflammation at the Heart of Heart Failure
Source : https://pubmed.ncbi.nlm.nih.gov/38340272/
Recent findings have shed light on the central role of bioactive lipids, specifically lysophosphatidic acid (LPA) and ceramides, in heart failure pathology. Traditional studies have emphasized factors such as hypoxia-mediated...
This review aimed to bridge the gap between basic research and clinical practice by providing actionable insights and a foundation for the development of targeted therapies that could mitigate the effects of bioactive lipids on heart failure.
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