Comprehensive chemical profiling of the flowers of Citrus aurantium L. var. amara Engl. and uncovering the active ingredients of lipid lowering
Source : https://www.sciencedirect.com/science/article/abs/pii/S0731708522000425?via=ihub
The structure-DPIs-NL library was developed for characterization of FCAVA. * A total of 228 constituents were characterized in FCAVA. * A simple method for quantification of 19 flavonoids in FCAVA...
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Conclusion: Overall, these findings indicated the potential of FCAVA in the development of functional food or medicine for the prevention and treatment of hyperlipidemia, which could be considered for the improvement of quality standardization of FCAVA.
Long-term effects of evolocumab in participants with HIV and dyslipidemia: results from the open-label extension period - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35025817/
doi: 10.1097/QAD.0000000000003175. Online ahead of print. 1 Sorbonne Université, GRC no.
Conclusion: Long-term administration of evolocumab lowered LDL-C and non-HDL-C, allowing more PWH to achieve recommended lipid goals with no serious adverse events.
Sex differences in low-density lipoprotein cholesterol reduction with PCSK9 inhibitors in real world patients: the LIPID-REAL Registry - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34983910/
doi: 10.1097/FJC.0000000000001205. Online ahead of print. 1 Cardiology Department. Hospital Universitario de San Juan. Alicante, Spain Unidad de Investigación en Cardiología. Fundación para el Fomento de la Investigación Sanitaria y...
Conclusion: This multicentre and retrospective registry of real-world patients treated with PCSK9 inhibitors highlights significant gender differences in LDLc reduction.
Molecular genetics for familial hypercholesterolemia
Source : https://imrpress.com/journal/RCM/23/1/10.31083/j.rcm2301004
IMR Press is a leading publisher of open access peer-reviewed biomedical and life sciences journals. We aim to facilitate the dissemination of high-quality research in the area of biomedical science....
Conclusion/Relevance: "These results permit the following conclusions: (a) when participants were solely ascertained for abnormal LDL cholesterol level (>190 mg/dL), we identified an FH mutation in 25.05% of hypercholesterolemic patients. These sequencing yelds are partially overlapping with other previous screening studies [7, 8]; (b) CAD...
Laparoscopic diagnosis of idiopathic left ovarian vein thrombosis in a 27-year-old woman - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35096407/
Idiopathic left ovarian vein thrombosis was diagnosed in a 27-year-old woman at the time of a diagnostic laparoscopy performed because of a suspected ovarian torsion. The diagnosis was confirmed by...
Relevance: During follow-up it became clear that the patient was already diagnosed with familial hypercholesterolemia before the occurrence of the ovarian vein thrombosis. It remains unclear if familial hypercholesterolemia played a role in the occurrence of ovarian vein thrombosis in our patient.