Key Points
• Conclusion/Relevance: “People with a small asymptomatic AAA are at high risk of MVE [major vascular events] and PVE [peripheral vascular events]. This study provides evidence of the possible benefits and allowable expense for a cost effective intensive LDL-C lowering programme in this population.”
• The aims of this portion of an ongoing prospective study out of Australia were to assess the incidence of major vascular event (MVE) and peripheral vascular events (PVE) in 583 people with a small asymptomatic abdominal aortic aneurysm (AAA) and model the potential benefits and expense of an intensified low density lipoprotein cholesterol (LDL-C) lowering program.
• “Results suggest that a mean reduction of 1 mmol/L in LDL-C could reduce absolute risk of MVE and PVE by 6.5% and 5.3%, respectively,” wrote the authors. “It was estimated that the maximum allowable expense for a cost effective LDL-C lowering programme would be between $1 239 AUD (€768) and $1 582 AUD (€981) per person per annum over a five year period.”
• Conclusion/Relevance: “People with a small asymptomatic AAA are at high risk of MVE [major vascular events] and PVE [peripheral vascular events]. This study provides evidence of the possible benefits and allowable expense for a cost effective intensive LDL-C lowering programme in this population.”
• The aims of this portion of an ongoing prospective study out of Australia were to assess the incidence of major vascular event (MVE) and peripheral vascular events (PVE) in 583 people with a small asymptomatic abdominal aortic aneurysm (AAA) and model the potential benefits and expense of an intensified low density lipoprotein cholesterol (LDL-C) lowering program.
• “Results suggest that a mean reduction of 1 mmol/L in LDL-C could reduce absolute risk of MVE and PVE by 6.5% and 5.3%, respectively,” wrote the authors. “It was estimated that the maximum allowable expense for a cost effective LDL-C lowering programme would be between $1 239 AUD (€768) and $1 582 AUD (€981) per person per annum over a five year period.”