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Empagliflozin reduced the risk for first and total HF hospitalization, irrespective of LVEF or congestion or both.

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Low Density Neutrophils and Neutrophil Extracellular Traps (NETs) Are New Inflammatory Players in Heart Failure

Low Density Neutrophils and Neutrophil Extracellular Traps (NETs) Are New Inflammatory Players in Heart Failure

Source : https://pubmed.ncbi.nlm.nih.gov/38555028/

HFpEF patients present higher levels of circulating LDNs and NETs related activities, which are the highest in the context of acute HF decompensation.

Patients with HFpEF presented higher levels of circulating low-density neutrophils and neutrophil extracellular trap–related activities.

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Sympathetic Neural Control at Rest and During the Cold Pressor Test in Patients With Heart Failure With Preserved Ejection Fraction

Sympathetic Neural Control at Rest and During the Cold Pressor Test in Patients With Heart Failure With Preserved Ejection Fraction

Source : https://pubmed.ncbi.nlm.nih.gov/38385250/

Despite augmented resting MSNA burst frequency, burst incidence was not significantly different between groups, and sympathetic baroreflex sensitivity was reduced in patients with HFpEF. Furthermore, patients had preserved sympathetic reactivity...

Despite augmented resting muscle sympathetic nerve activity burst frequency, burst incidence was not significantly different between groups, and sympathetic baroreflex sensitivity was reduced in patients with heart failure with preserved ejection fraction.

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Significant associations between the intervention and self-care maintenance, self-care management, self-care confidence, and heart failure knowledge were found.

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Fluid and Salt Balance Are Things We Often Overlook: Could Our Understanding of Fluid Dynamics Change How We Tackle Heart Failure?

Fluid and Salt Balance Are Things We Often Overlook: Could Our Understanding of Fluid Dynamics Change How We Tackle Heart Failure?

Source : https://pubmed.ncbi.nlm.nih.gov/38486616/

Fluid and Salt Balance Are Things We Often Overlook: Could Our Understanding of Fluid Dynamics Change How We Tackle Heart failure?

Limiting intake may mitigate the need for such aggressive strategies that could prove detrimental to renal function, systemic blood pressures, and worsen extracardiac symptoms such as cramping or dizziness.

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