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State of precision medicine for heart failure with preserved ejection fraction in a new therapeutic age - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39844745/
Heart failure with preserved ejection fraction (HFpEF) is defined by heart failure (HF) with a left ventricular ejection fraction (LVEF) of at least 50%. HFpEF has a complex and heterogeneous...
HFpEF is a complex, heterogeneous condition challenging to diagnose. Algorithms (H2FPEF, HFA-PEFF), phenotype clustering, and SGLT2 inhibitors aid management, while future research explores precision diagnostics and novel therapies.
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Chronic Heart Failure and Coronary Artery Disease: Pharmacological Treatment and Cardiac Rehabilitation - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40005328/
Coronary artery disease is the leading cause of acute and chronic heart failure. Patients with heart failure and ischemic heart disease need a tailored assessment to define the appropriate treatment,...
Coronary artery disease drives heart failure. Comprehensive assessment and multidisciplinary management, including pharmacological therapy and cardiac rehabilitation, improve survival, reduce hospitalizations, and support tailored, guideline-directed care for fragile patients.
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10mo
Extracorporeal cardiopulmonary resuscitation for refractory cardiac arrest - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40456239/
When conventional cardiopulmonary resuscitation (CCPR) cannot restore spontaneous circulation, the initiation of venoarterial extracorporeal membrane oxygenation during refractory cardiac arrest-known as extracorporeal CPR (ECPR)-might restore circulation and adequate tissue oxygenation....
ECPR, used when CCPR fails, can restore circulation and improve survival but faces limitations due to complexity, cost, and risks. Outcomes depend on patient factors, timing, and procedural effectiveness.
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10mo
Maternal Serum Folate During Pregnancy and Congenital Heart Disease in Offspring - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39388179/
In this case-control study of CHD, low maternal serum folate levels in early to midpregnancy were associated with an increased CHD risk in offspring, and excessively high folate levels were...
Maternal folate levels showed a U-shaped association with CHD risk in offspring; both low and high levels increased risk, especially with concurrent vitamin B12 deficiency or elevated homocysteine.
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