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Management strategies in heart failure with preserved ejection fraction

Management strategies in heart failure with preserved ejection fraction

Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075717/

Language: English | German The diagnosis and therapy of heart failure with preserved ejection fraction (HFpEF) remain challenging. Currently, there are ongoing discussions on whether the diagnosis of HFpEF should...



Conclusion: Overall, this review aims to enhance the knowledge on the diagnostic processes and best treatments available for HFpEF patients.



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New therapies for the treatment of heart failure with preserved ejection fraction - PubMed

New therapies for the treatment of heart failure with preserved ejection fraction - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/35524990/

doi: 10.1093/ajhp/zxac129. Online ahead of print. 1 South University School of Pharmacy, Savannah, GA, and St. Joseph's/Candler Health System, Savannah, GA, USA. 2 St. Joseph's/Candler Health System, Savannah, GA, USA....



Conclusion: The PARAGON-HF and EMPEROR-Preserved trials will serve as the foundation for a new era in the treatment of HFpEF.

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Healthcare resource utilization and associated costs | CEOR

Healthcare resource utilization and associated costs | CEOR

Source : https://www.dovepress.com/healthcare-resource-utilization-and-associated-costs-in-new-users-of-e-peer-reviewed-fulltext-article-CEOR

In Germany, the current estimates of the prevalence of diabetes range between 7.2% (population aged 18 to 79 years) based on health examination surveys of the Robert Koch Institute and...



Conclusion: Although the individual clinical patient profile and physician assessment are paramount in treatment decisions, substantial differences in the economic impact of different antidiabetic therapies should be considered.

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Empagliflozin in kidney transplant recipients with chronic kidney disease G3a-4 and metabolic syndrome: Five Japanese cases - PubMed

Empagliflozin in kidney transplant recipients with chronic kidney disease G3a-4 and metabolic syndrome: Five Japanese cases - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/35501824/

Empagliflozin showed some positive effects in 4 cases with better renal function than CKD stage 4. Further studies will be required to clarify the efficacy and safety of SGLT2 inhibitors...



Conclusion: Empagliflozin showed some positive effects in 4 cases with better renal function than CKD stage 4. Further studies will be required to clarify the efficacy and safety of SGLT2 inhibitors in a larger group of patients with similar medical conditions.

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    Key Points • Source: BMC Nephrology • Conclusion: “Empagliflozin showed some positive effects in 4 cases with better renal function than CKD [chronic kidney disease] stage 4. Further studies will Show More
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Sodium-Glucose Cotransporter-2 Inhibitors in Heart Failure with Reduced Ejection Fraction: Current Evidence and Future Perspectives - PubMed

Sodium-Glucose Cotransporter-2 Inhibitors in Heart Failure with Reduced Ejection Fraction: Current Evidence and Future Perspectives - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/35510595/

Solid clinical data support the current recommendations to use empagliflozin or dapagliflozin in HFrEF. The underlying mechanisms likely include changes in cardiac and intrarenal haemodynamic. Yet, these mechanisms do not...


Conclusions: Solid clinical data support the current recommendations to use empagliflozin or dapagliflozin in HFrEF. The underlying mechanisms likely include changes in cardiac and intrarenal haemodynamic. Yet, these mechanisms do not seem to solely explain the observed magnitude of clinical effect with SGLT2 inhibitors in HFrEF and other...

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